From:  Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study
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Placenta OPRM1 DNA methylation and NOWS pharmacologic treatment. Average placental OPRM1 methylation levels for CpG sites for the 64 opioid subjects based on NOWS pharmacologic treatment (n = 49) versus no treatment (n = 15). There were no statistically significant differences in univariate or multivariate analyses