| 1 |
2023 |
Ana C. Valencia-Olvera, Deebika Balu, Naomi Faulk, Aspasia Amiridis, Yueting Wang, Christine Pham, Eva Avila-Munoz, Jason M. York, Gregory R.J. Thatcher, Mary Jo LaDu. Inhibition of ACAT as a Therapeutic Target for Alzheimer's Disease Is Independent of ApoE4 Lipidation, Neurotherapeutics. 2023; 20: 1120.
https://doi.org/10.1007/s13311-023-01375-3 |
| 2 |
2023 |
Eugenia Trushina, T.K.O. Nguyen, S. Trushin. Modulation of Mitochondrial Function as a Therapeutic Strategy for Neurodegenerative Diseases, The Journal of Prevention of Alzheimer's Disease. 2023; 10: 675.
https://doi.org/10.14283/jpad.2023.108 |
| 3 |
2024 |
Anurag Thapliyal, Shweta, Shashank Kumar Maurya. 2024; 365.
https://doi.org/10.1007/978-981-97-4288-2_14 |
| 4 |
2025 |
Jenna Parker, Jose M. Moris, Lily C. Goodman, Vineet K. Paidisetty, Vicente Vanegas, Haley A. Turner, Daniel Melgar, Yunsuk Koh. A multifactorial lens on risk factors promoting the progression of Alzheimer’s disease, Brain Research. 2025; 1846: 149262149262.
https://doi.org/10.1016/j.brainres.2024.149262 |
| 5 |
2025 |
Patricia Alves de Castro, Daniel Yuri Akiyama, Camila Figueiredo Pinzan, Thaila Fernanda dos Reis, Endrews Delbaje, Peter Rocha, Mario Augusto Izidoro, Sérgio Schenkman, Shinya Sugimoto, Norio Takeshita, Karin Steffen, Jessica L. Aycock, Stephen K. Dolan, Antonis Rokas, Taícia Fill, Gustavo H. Goldman, Alexandre Alanio.
Aspergillus fumigatus
secondary metabolite pyripyropene is important for the dual biofilm formation with
Pseudomonas aeruginosa
, mBio. 2025; 16: e00363-25.
https://doi.org/10.1128/mbio.00363-25 |
| 6 |
2022 |
A. Martín-Montes, M. Recuero, I. Sastre, E. Vilella, M. Rosich-Estragó, M. Atienza, J.L. Cantero, A. Frank-García, M.J. Bullido. Cholesterol dysregulation in peripheral blood mononuclear cells of Alzheimer's disease, Journal of Neuroimmunology. 2022; 373: 577996577996.
https://doi.org/10.1016/j.jneuroim.2022.577996 |
| 7 |
2023 |
Adrianna L. De La Torre, Thao N. Huynh, Catherine C. Y. Chang, Darcy B. Pooler, Dylan B. Ness, Lionel D. Lewis, Sanjana Pannem, Yichen Feng, Kimberley S. Samkoe, William F. Hickey, Ta Yuan Chang. Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer’s Disease Mice, International Journal of Molecular Sciences. 2023; 24: 11013.
https://doi.org/10.3390/ijms241311013 |
| 8 |
2023 |
Taylor C. Harned, Radu V. Stan, Ze Cao, Rajarshi Chakrabarti, Henry N. Higgs, Catherine C. Y. Chang, Ta Yuan Chang. Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity, International Journal of Molecular Sciences. 2023; 24: 5525.
https://doi.org/10.3390/ijms24065525 |
| 9 |
2023 |
Andrea Schiffmann, Lena Ahlswede, Gerald Gimpl. Reversible translocation of acyl-CoA:cholesterol acyltransferase (ACAT) between the endoplasmic reticulum and vesicular structures, Frontiers in Molecular Biosciences. 2023; 10: 1258799.
https://doi.org/10.3389/fmolb.2023.1258799 |
| 10 |
2023 |
Adrianna L. De La Torre, Thao N. Huynh, Catherine C.Y. Chang, Darcy B. Pooler, Dylan Ness, Lionel Lewis, Sanjana Pannem, Yichen Feng, Kimberley S. Samkoe, William F. Hickey, Ta Yuan Chang. 2023;
https://doi.org/10.1101/2023.05.02.539100 |
| 11 |
2024 |
Thao N. Huynh, Matthew C. Havrda, George J. Zanazzi, Catherine C. Y. Chang, Ta Yuan Chang. Inhibiting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Myelin Debris-Treated Microglial Cell Lines Activates the Gene Expression of Cholesterol Efflux Transporter ABCA1, Biomolecules. 2024; 14: 1301.
https://doi.org/10.3390/biom14101301 |
| 12 |
2024 |
Jordan A Bairos, Uche Njoku, Maria Zafar, May G Akl, Lei Li, Gunes Parlakgul, Ana Paula Arruda, Scott B Widenmaier. 2024;
https://doi.org/10.1101/2024.01.20.576345 |
| 13 |
2025 |
Sijia He, Ziying Xu, Xianlin Han. Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications, Molecular Neurodegeneration. 2025; 20: 11.
https://doi.org/10.1186/s13024-025-00803-6 |
| 14 |
2022 |
Oscar M. Muñoz Herrera, Angela M. Zivkovic. Microglia and Cholesterol Handling: Implications for Alzheimer’s Disease, Biomedicines. 2022; 10: 3105.
https://doi.org/10.3390/biomedicines10123105 |
| 15 |
2023 |
Cecilia Vitali, Chiara Pavanello, Marta Turri, Sissel Lund-Katz, Michael C. Phillips, Alberico Luigi Catapano, Andrea Baragetti, Giuseppe Danilo Norata, Fabrizio Veglia, Laura Calabresi. Apolipoprotein E isoforms differentially affect LCAT-dependent cholesterol esterification, Atherosclerosis. 2023; 382: 117266117266.
https://doi.org/10.1016/j.atherosclerosis.2023.117266 |
| 16 |
2022 |
Maximillian A. Rogers, Catherine C. Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver, Junghoon Lee, Peter Schroen, Mitchell Huang, Ta-Yuan Chang.
Acat1/Soat1
knockout extends the mutant
Npc1
mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells
, Proceedings of the National Academy of Sciences. 2022; 119: e2201646119.
https://doi.org/10.1073/pnas.2201646119 |
| 17 |
2023 |
Andrea Schiffmann, Lena Ahlswede, Gerald Gimpl. 2023;
https://doi.org/10.1101/2023.06.06.543826 |
| 18 |
2024 |
Jordan A. Bairos, Uche Njoku, Maria Zafar, May G. Akl, Lei Li, Gunes Parlakgul, Ana Paula Arruda, Scott B. Widenmaier. Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2024; 1869: 159512159512.
https://doi.org/10.1016/j.bbalip.2024.159512 |
