GF: Conceptualization, Investigation, Writing—original draft, Writing—review & editing. CG: Conceptualization, Validation, Supervision. Both authors read and approved the submitted version.
Conflicts of interest
Giampiero Francica, who is the Editorial Board Member of Exploration of Digestive Diseases, had no involvement in the decision-making or the review process of this manuscript. Cristiano Giardiello declares that he has no conflicts of interest.
Ethical approval
Hospital Health Management of Pineta Grande Hospital has exempted this case report presented by the Interventional Ultrasound Unit and the Department of Obesity Surgery from Ethical Committee review, as all medical procedures described are consistent with standard clinical practice (document reference no. 2024/192). The study followed the Declaration of Helsinki.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Informed consent to publication was obtained from relevant participants.
Availability of data and materials
The clinical records for this study can be found in the Digital Archive of Pinetagrande Hospital, which is available for consulting only after permission from Hospital Health Management of Pineta Grande Hospital (direzionesaniataria@pinetagrande.it).
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
References
Zhou XD, Chen QF, Yang W, Zuluaga M, Targher G, Byrne CD, et al. Burden of disease attributable to high body mass index: an analysis of data from the Global Burden of Disease Study 2021.EClinicalMedicine. 2024;76:102848. [DOI] [PubMed] [PMC]
Weiskirchen R, Lonardo A. How ‘miracle’ weight-loss semaglutide promises to change medicine but can we afford the expense?Br J Pharmacol. 2025;182:1651–70. [DOI] [PubMed]
Lonardo A, Singal AK. Duodenal mucosa resurfacing: the endoscopic silver bullet against metabolic disorders?Metab Target Organ Damage. 2025;5:13. [DOI]
Harrington S, Kang S, Telesca L, Cohen RV, Roux CWL. Long-term complications of significant weight loss: lessons learned from bariatric surgery.Metab Target Organ Damage. 2024;4:11. [DOI]
Schiavo L, De Stefano G, Persico F, Gargiulo S, Di Spirito F, Griguolo G, et al. A Randomized, Controlled Trial Comparing the Impact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment.Obes Surg. 2021;31:1514–23. [DOI] [PubMed] [PMC]
Alsabah S, Al Haddad E, Ekrouf S, Almulla A, Al-Subaie S, Al Kendari M. The safety and efficacy of the procedureless intragastric balloon.Surg Obes Relat Dis. 2018;14:311–7. [DOI] [PubMed]
Machytka E, Gaur S, Chuttani R, Bojkova M, Kupka T, Buzga M, et al. Elipse, the first procedureless gastric balloon for weight loss: a prospective, observational, open-label, multicenter study.Endoscopy. 2017;49:154–60. [DOI] [PubMed]
Jamal MH, Almutairi R, Elabd R, AlSabah SK, Alqattan H, Altaweel T. The Safety and Efficacy of Procedureless Gastric Balloon: a Study Examining the Effect of Elipse Intragastric Balloon Safety, Short and Medium Term Effects on Weight Loss with 1-Year Follow-Up Post-removal.Obes Surg. 2019;29:1236–41. [DOI] [PubMed]
Genco A, Ernesti I, Ienca R, Casella G, Mariani S, Francomano D, et al. Safety and Efficacy of a New Swallowable Intragastric Balloon Not Needing Endoscopy: Early Italian Experience.Obes Surg. 2018;28:405–9. [DOI] [PubMed]
Ienca R, Al Jarallah M, Caballero A, Giardiello C, Rosa M, Kolmer S, et al. The Procedureless Elipse Gastric Balloon Program: Multicenter Experience in 1770 Consecutive Patients.Obes Surg. 2020;30:3354–62. [DOI] [PubMed] [PMC]
Vantanasiri K, Matar R, Beran A, Jaruvongvanich V. The Efficacy and Safety of a Procedureless Gastric Balloon for Weight Loss: a Systematic Review and Meta-Analysis.Obes Surg. 2020;30:3341–6. [DOI] [PubMed]
Caballero A, Giardiello C, Quartararo G, Formiga A, Rosa M, Schiano di Cola R, et al. Multicenter Retrospective Analysis of Consecutive Swallowable Gastric Balloon Treatments in a Community Obesity Care Setting.Obes Surg. 2025;35:4737–43. [DOI] [PubMed]
Loo JH, Lim YH, Seah HL, Chong AZQ, Tay KV. Intragastric Balloon as Bridging Therapy Prior to Bariatric Surgery for Patients with Severe Obesity (BMI ≥ 50 kg/m2): a Systematic Review and Meta-analysis.Obes Surg. 2022;32:489–502. [DOI] [PubMed]
Hay D, Ryan G, Somasundaram M, Yip V, Navaratne L. Laparoscopic management of a migrated intragastric balloon causing mechanical small bowel obstruction: a case report and review of the literature.Ann R Coll Surg Engl. 2019;101:e172–7. [DOI] [PubMed] [PMC]
de Sio I, Funaro A, Vitale LM, Niosi M, Francica G, Federico A, et al. Ultrasound-guided percutaneous biopsy for diagnosis of gastrointestinal lesions.Dig Liver Dis. 2013;45:816–9. [DOI] [PubMed]
Francica G, Giardiello C, Iodice G, Cristiano S, Scarano F, Delle Cave M, et al. Ultrasound as the imaging method of choice for monitoring the intragastric balloon in obese patients: normal findings, pitfalls and diagnosis of complications.Obes Surg. 2004;14:833–7. [DOI] [PubMed]
