Primary antibodies were used in this study.
| Protein | Catalog number | Company | Dilution |
|---|---|---|---|
| p-SMAD2 | 138D4 | Cell Signaling Technologies | 1:1,000 |
| SMAD2 | D43B4 | Cell Signaling Technologies | 1:1,000 |
| β-actin | A3854 | Sigma-Aldrich | 1:10,000 |
| MRP2 | sc-59611 | Santa Cruz Biotechnology | 1:200 |
| MRP3 | 14182 | Cell Signaling Technologies | 1:1,000 |
| MRP4 | 12705 | Cell Signaling Technologies | 1:1,000 |
We thank Dr. Alejandro Escobedo-Calvario for supporting the preparation of the manuscript and the graphical abstract. Secretaria de Ciencia, Humanidades, Tecnología e Innovación (SECIHTI) [scholarship 2022-000018-02NACF-16729]. The SECIHTI wasn’t involved in any role related to this study; it only provided Natanel German-Ramirez with the scholarship for his Ph.D. studies.
NGR: Conceptualization, Investigation, Formal analysis, Validation, Writing—original draft, Writing—review & editing. MGR: Visualization, Writing—original draft, Writing—review & editing. GIDG: Writing—review & editing. VSA, LBO, BPA, and RUML: Methodology, Writing—review & editing. FMR and APA: Resources, Methodology. MCGR: Conceptualization, Funding acquisition, Writing—review & editing. ASN: Conceptualization, Methodology, Supervision, Writing—review & editing. LEGQ: Conceptualization, Funding acquisition, Resources, Supervision, Project administration, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Luis E. Gomez-Quiroz, a member of the Editorial Board of Exploration of Digestive Diseases, was not involved in the decision-making or the review process of this manuscript. The other authors declare no conflicts of interest.
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The data supporting this study’s findings are available from the corresponding author on reasonable request.
This work was supported by Fundación Mexicana para la Salud Hepática [Antonio Ariza Cañadilla grant 2022]. The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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