Possible associations between antidepressants and infection risk
| Mechanism or outcome | Evidence |
|---|---|
| Immunosuppression | Reduced leukocyte count [131] Reduced immune response in burns patients [132] Impaired tumor surveillance [140] |
| Increased colonization | Increased nasal bacterial colonization [138] |
| Increased infection risk | Infections in general [133] Post-operative infections [134] Respiratory infections [136] Clostridium difficile infection [135] |
| Worse outcomes after infection | Increased mortality in hospitalized patients [137] |
| Antimicrobial resistance | Selection pressure towards antibiotic resistance in Escherichia coli [139] |
RPR: Conceptualization, Methodology, Writing—original draft, Writing—review & editing. The author has read and approved the submitted version.
The author declares that he has no conflicts of interest.
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© The Author(s) 2024.