Innate and adaptive immune response in AD
Disease | Innate immunity | Adaptive immunity |
---|---|---|
AD | Chemokines, cytokines, and complements are all expressed in amyloid plaques. In vitro, Aβ induces innate immune expression. Aβ clearance is aided by microglia | As a therapeutic approach, activation of the adaptive immune system against Aβ peptide will aid clearance |
Thanks are due to CEHTI and the bioinformatics lab of the Department of Biotechnology and Bioinformatics, Jaypee University of Information technology, Solan, Himachal Pradesh, India for the technical help.
TRS: Conceptualization, Writing—review & editing. AS: Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
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© The Author(s) 2023.