Patients’ clinical characteristics

Clinical characteristics Patients n %
Sex Male 48 73.8
Female 17 26.2
Histology Squamous 28 43.1
Non-squamous 37 56.9
Age at diagnosis < 70 years 35 53.8
≥ 70 years 30 46.2
Smoking Smokers 16 24.6
Non-smokers 4 6.2
Former smokers 45 69.2
PS-ECOG (at start of immunotherapy) ≥ 2 9 13.8
< 2 56 86.2
Metastases sites Bone 28 43.1
Pulmonary 47 72.3
Adrenal 15 23.1
Lymph nodes 51 78.5
Pleural 22 33.8
Cerebral 8 12.3
Liver 9 13.8
Disease characteristics Measurable 21 32.3
Not measurable 44 67.7
Extra-thoracic localization of disease 33 50.8
Thoracic localization of disease 32 49.2
Number of sites of metastases < 4 48 73.8
≥ 4 17 26.2
Immunotherapy First line 10 15.4
Second line 55 84.6
mOS 23.3 months
mPFS2 5.3 months