Table Info

Table 4.

Class I HDACis undergoing clinical trials [23]

ZBG class	Name	Structure	Clinical trial phase	Indications
Benzamide	Entinostat		2	Breast cancer [24] and elanoma [25]
	RDN-929		1	Healthy patients [26]
	Mocetinostat		1	Lymphoma [27] and lung cancer [28]
Hydroxamic acid	Pracinostat		2	AML [29]
	Resminostat		1/2	Colorectal CTCL [30]
	Givinostat		2	Polycythemia vera [31], DMD [32], and arthritis [33, 34]
	Remetinostat		2	CTCL [35]
Thiol	OKI-179	Structure undisclosed	1	Solid tumors [36]

AML: acute myeloid leukemia; CTCL: cutaneous T-cell lymphoma; DMD: duchenne muscular dystrophy

Declarations

Author contributions

DIA, EDdA, and PTG: Conceptualization. DIA, NHP, and LSH: Investigation, Data collection. DIA: Writing—original draft. DIA, EDdA, OHK, RM, NHP, LSH, and PTG: Writing—review & editing. DIA, EDdA, OHK, RM, and PTG: Validation. DIA and PTG: Supervision. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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