Table Info

Table 1.

A partial list of anticancer drugs based on increased ROS production

Drug (name)	Cancer treated	Mechanism to increase ROS	References
Platinum drugs	Breast cancer (in combination with PARP inhibitors)	ROS-dependent DNA damage	[8, 9]
Imatinib	Melanoma	Loss of mitochondrial membrane potential	[10]
Doxorubicin	Kaposi’s sarcoma, breast, and bladder cancer	Fenton’s reaction and electron leakage	[11]
5-Fluorouracil	Colon and rectal cancer	P53 dependent ROS	[12, 13]

PARP: poly (ADP-ribose) polymerase

Declarations

Author contributions

RS: Conceptualization, Supervision. IGC: Supervision. PG: Conceptualization, Data curation, Formal analysis, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.

Conflicts of interest

The authors declare that they have no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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