• Online First:
    3articles
    Sort by
    Latest
    Open Access
    Original Article
    Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer
    Aim: Tamoxifen (TAM) resistance remains a clinical issue in breast cancer. The authors previously reported that 15-hydroxyprostaglandin dehydrogenase (HPGD) was significantly downregulated in tamox...
    Milene Volpato ... Valerie Speirs
    Online First: October 19, 2020 Explor Target Antitumor Ther. 2020;1:Online First
    DOI: https://doi.org/10.37349/etat.2020.00021
    View:119
    Download:6
    Times Cited: 0
    Open Access
    Review
    Current strategies for the design of PROTAC linkers: a critical review
    PROteolysis TArgeting Chimeras (PROTACs) are heterobifunctional molecules consisting of two ligands; an “anchor” to bind to an E3 ubiquitin ligase and a “warhead” to bind to a protein of interest, connected by a chemical linker...
    Robert I. Troup ... Matthias G. J. Baud
    Online First: October 11, 2020 Explor Target Antitumor Ther. 2020;1:Online First
    DOI: https://doi.org/10.37349/etat.2020.00018
    This article belongs to the special issue Proteolysis Targeting Chimera (PROTAC)
    View:324
    Download:49
    Times Cited: 0
    Open Access
    Review
    Diagnostic and prognostic role of liquid biopsy in non-small cell lung cancer: evaluation of circulating biomarkers
    Lung cancer is still one of the main causes of cancer-related death, together with prostate and colorectal cancers in males and breast and colorectal cancers in females. The prognosis for non-small ...
    Giovanni Vicidomini ... Mario Santini
    Online First: October 09, 2020 Explor Target Antitumor Ther. 2020;1:Online First
    DOI: https://doi.org/10.37349/etat.2020.00020
    This article belongs to the special issue Liquid Biopsy in Thoracic Cancer
    View:125
    Download:5
    Times Cited: 0