ANCA-MPO: antineutrophil cytoplasmic antibody specific for myeloperoxidase; ANCA-PR3: antineutrophil cytoplasmic antibody specific for proteinase 3; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; hpf: high power field.
Declarations
Author contributions
TMR: Conceptualization, Project administration, Writing—review & editing, Funding acquisition. ENV: Data curation, Writing—original draft. KSN: Visualization, Writing—review & editing. EIAA: Methodology. SVG: Methodology. ANS: Conceptualization, Project administration. AML: Supervision, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
There are no conflicts of interest.
Ethical approval
The study of Neutrophil activation in ANCA-associated vasculitis was approved by the local ethics committee of the V.A. Nasonova Research Institute of Rheumatology, protocol No. 20 dated October 12, 2023. The local ethics committee of the V.A. Nasonova Research Institute of Rheumatology confirmed that formal approval was not required for this case report. The study complies with the Declaration of Helsinki.
Consent to participate
Informed consent to participate in the study was obtained from the participants.
Consent to publication
Not applicable.
Availability of data and materials
The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified.
Funding
The study was conducted with the support of the Russian Science Foundation (RSF) grant No. 25-25-00245 “Markers of NETosis in Immunoinflammatory Rheumatic Diseases.” The article was prepared within the framework of the basic scientific topic № RК 125020501434-1. Although the study of netosis in this patient was conducted as part of a fundamental study, the funders had no role in the patient’s examination, study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Open Exploration maintains a neutral stance on jurisdictional claims in published institutional affiliations and maps. All opinions expressed in this article are the personal views of the author(s) and do not represent the stance of the editorial team or the publisher.
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