Table Info

Table 1.

TRP channels and their functions in different cancers

Family	Members	Cancer type	Effects	References
TRPC	TRPC1	Colorectal cancer (CRC)	Enhanced cell proliferation, migration, invasion, and metastasis and apoptosis resistance	[32, 33]
	TRPC3	Gastric cancer	Tumorigenesis	[34]
	TRPC3	Breast cancer	Enhanced proliferation and apoptosis resistance	[35]
	TRPC5	CRC	Reduction in cancer differentiation	[36]
	TRPC5	Breast cancer	Chemotherapeutic resistance	[37]
	TRPC6	Hepatocellular carcinoma	Enhanced migration and invasion	[38]
		Breast cancer	Proliferation, migration, and invasion	[39]
		Oesophageal cancer	Essential for G2 phase progression	[40]
TRPV	TRPV2	Gastric cancer	Gastric cancer	[41]
	TRPV4	Gastric cancer	Enhanced proliferation, migration, and invasion	[42]
	TRPV6	Breast cancer	Tumor metastasis	[43]
TRPM	TRPM3	Clear cell renal cell carcinoma (RCC)	Tumor growth	[44]
	TRPM4	Prostate cancer	Enhanced proliferation	[45]
	TRPM7	Ovarian cancer	EMT and enhanced proliferation	[46, 47]

TRPC: TRP canonical

Declarations

Author contributions

TX, SC, JH, and ZL conceptualized the manuscript; TX, SC, and JH wrote this review; PW, HW, and ZL revised the manuscript. All authors have read and approved the submitted version of the manuscript.

Conflicts of interest

The authors declare that there are no conflicts of interest.

Ethical approval

Not applicable.

Consent to participate

Not applicable.

Consent to publication

Not applicable.

Availability of data and materials

Not applicable.

Funding

Not applicable.

Copyright

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