From:  Safety and efficacy of delivering systemic treatments concomitantly with whole-brain radiotherapy: a prospective, observational, single-institution study

 Grade ≥ 3 acute toxicity by systemic therapy group.

Therapy groupGR ≥ 3 toxicityTotalp-value
NoYes
Non systemicNumber of patients567630.071
% within therapy group88.9%11.1%100.0%
SystemicNumber of patients27936
% within therapy group75.0%25.0%100.0%
TotalNumber of patients831699
% within therapy group83.8%16.2%100.0%

GR: grade.