Model parameter estimates for the Cox proportional hazard model for time to intracranial progression.
| Stratification factors | B | SE | Wald | df | p-value | HR | 95% CI for HR | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | |||||||
| Therapy group | –0.183 | 0.470 | 0.151 | 1 | 0.698 | 0.833 | 0.332 | 2.094 |
| Number of brain metastases | 0.731 | 0.348 | 4.414 | 1 | 0.036 | 2.077 | 1.050 | 4.109 |
| Fractionation | 1.593 | 0.708 | 5.065 | 1 | 0.024 | 4.917 | 1.228 | 19.682 |
| Co-existence of systemic disease | 0.096 | 0.451 | 0.045 | 1 | 0.832 | 1.100 | 0.455 | 2.663 |
B: regression coefficient (beta); SE: standard error; df: degrees of freedom; HR: hazard ratio; CI: confidence interval.
Maria P: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing—original draft. KP: Conceptualization, Supervision, Validation, Writing—review & editing. Michalis P: Conceptualization, Formal analysis, Software, Visualization, Writing—review & editing. STN: Conceptualization, Data curation, Investigation, Project administration, Writing—review & editing. ZL: Conceptualization, Data curation, Investigation, Project administration, Writing—review & editing. DA: Conceptualization, Data curation, Investigation, Writing—review & editing. Christina A: Conceptualization, Data curation, Investigation, Writing—review & editing. Christos A: Conceptualization, Data curation, Investigation, Writing—review & editing. CP: Conceptualization, Methodology, Resources, Software, Supervision, Validation, Writing—review & editing. VK: Conceptualization, Formal analysis, Methodology, Software, Supervision, Validation, Writing—review & editing. AZ: Conceptualization, Methodology, Resources, Supervision, Validation, Writing—review & editing. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
The Ethics Committee of Aretaieion University Hospital of Athens, Greece, approved the study. The study received the following protocol number: 34/20-04-18. This study was conducted in accordance with the Declaration of Helsinki.
Informed consent to participate in the study was obtained from all participants.
Not applicable.
The datasets supporting the findings of this study are available from the corresponding author upon reasonable request.
Not applicable.
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