The effects of po-TACE treatment on HCC prognosis stratified by ADAs
| ADA | Po-TACE treatment | OS | RFS | ||
|---|---|---|---|---|---|
| DR (95% CI)a | Ptrend | TRR (95% CI)a | Ptrend | ||
| Low | Yes vs. no | 0.84 (0.58–1.20) | 0.33 | 0.84 (0.58–1.23) | 0.37 |
| High | Yes vs. no | 0.36 (0.24–0.53) | 2.67 × 10–7 | 0.40 (0.28–0.59) | 2.00 × 10–6 |
a Adjusted by age, sex, race, HBV and HCV status, smoking and drinking status, AFP, liver cirrhosis, and tumor grade. Ptrend: P value is calculated by trend test in the models
We thank Dr. Qiu-Xiang Liang, Dr. Yun Yi, Yun Xia, Yong-Zhi Huang, and Dr. Yuan-Feng Zhou for sample collection and management, Dr. Hua Huang for molecular biochemical technique.
LYH and QQL: Methodology, Formal analysis, Data curation, Writing—review & editing. QYS: Investigation, Resource, Writing—review & editing. XYZ: Investigation, Formal analysis, Writing—review & editing. XDL: Conceptualization, Funding acquisition, Supervision, Project administration, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
The authors declare that they have no conflicts of interest.
The collection of removed tumor samples and clinicopathological information are approved by the Ethics Committee of Youjiang Medical University for Nationalities, China (No. AYJM20150118) and comply with the Declaration of Helsinki.
Informed consent to participate in the study was obtained from all participants.
Not applicable.
Not applicable.
This study was supported in part by Guangxi Training Program for Medical High-level Academic Leaders [Guiweikejiaofa (2020)-15], Bose Talent Highland [2020-3-2], Building Projects from the Key Laboratory of Molecular Pathology (Hepatobiliary Diseases) of Guangxi [Guiweikejiaofa (2020)-17] and the Key Laboratory of Tumor Molecular Pathology of Guangxi Colleges & Universities [Guijiaokeyan (2022)-10], and Clinical Key Specialty Building Project (For Pathology) of Guangxi [Guiweiyifa (2022)-21]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2023.