The clinicopathological features of HCC cases with or without po-TACE treatment
Variable
Controls (n = 160)
Po-TACEs (n = 158)
χ2
P
n
%
n
%
Age (years old)a
48
91
56.9
88
55.7
0.045
0.832
> 48
69
43.1
70
44.3
Gender
Male
113
70.6
102
64.6
1.337
0.248
Female
47
29.4
56
35.4
Race
Han
93
58.1
79
50.0
2.113
0.146
Zhuang
67
41.9
79
50.0
HBV status
Negative
47
29.4
54
34.2
0.846
0.358
Positive
113
70.6
104
65.8
HCV status
Negative
146
91.3
137
86.7
1.674
0.196
Positive
14
8.8
21
13.3
Smoking status
No
121
75.6
121
76.6
0.040
0.841
Yes
39
24.4
37
23.4
Drinking status
No
113
70.6
122
77.2
1.790
0.181
Yes
47
29.4
36
22.8
AFP (ng/L)
20
57
35.6
59
37.3
0.101
0.750
> 20
103
64.4
99
62.7
Liver cirrhosis
No
37
23.1
40
25.3
0.208
0.648
Yes
123
76.9
118
74.7
ES gradeb
Low
80
50.0
88
55.7
1.036
0.309
High
80
50.0
70
44.3
MVD
No
55
34.4
56
35.4
0.040
0.842
Yes
105
65.6
102
64.6
a Age is grouped according to the average age of patients with HCC (47.94 years old 9.98 years old); b ES grade is divided into two groups: low grade (ES-I and -II grade) and high grade (ES-III and -IV grade). AFP: α-fetoprotein
Declarations
Acknowledgement
We thank Dr. Qiu-Xiang Liang, Dr. Yun Yi, Yun Xia, Yong-Zhi Huang, and Dr. Yuan-Feng Zhou for sample collection and management, Dr. Hua Huang for molecular biochemical technique.
Author contributions
LYH and QQL: Methodology, Formal analysis, Data curation, Writing—review & editing. QYS: Investigation, Resource, Writing—review & editing. XYZ: Investigation, Formal analysis, Writing—review & editing. XDL: Conceptualization, Funding acquisition, Supervision, Project administration, Writing—original draft, Writing—review & editing. All authors read and approved the submitted version.
Conflicts of interest
The authors declare that they have no conflicts of interest.
Ethical approval
The collection of removed tumor samples and clinicopathological information are approved by the Ethics Committee of Youjiang Medical University for Nationalities, China (No. AYJM20150118) and comply with the Declaration of Helsinki.
Consent to participate
Informed consent to participate in the study was obtained from all participants.
Consent to publication
Not applicable.
Availability of data and materials
Not applicable.
Funding
This study was supported in part by Guangxi Training Program for Medical High-level Academic Leaders [Guiweikejiaofa (2020)-15], Bose Talent Highland [2020-3-2], Building Projects from the Key Laboratory of Molecular Pathology (Hepatobiliary Diseases) of Guangxi [Guiweikejiaofa (2020)-17] and the Key Laboratory of Tumor Molecular Pathology of Guangxi Colleges & Universities [Guijiaokeyan (2022)-10], and Clinical Key Specialty Building Project (For Pathology) of Guangxi [Guiweiyifa (2022)-21]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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