Quantitative results of the analyzed biomarkers in the study population
| Biomarker | Primary tumor | Metastasis | |
|---|---|---|---|
| MET (% positive cells) | Mean | 44.6 | 72.4 |
| Median | 50 | 90 | |
| Range | 0–100 | 0–100 | |
| MET (number of cases) | Negative | 2 | 1 |
| 1 (+) | 12 | 3 | |
| 2 (++) | 7 | 7 | |
| 3 (+++) | 4 | 14 | |
| mTOR (% positive cells) | Mean | 28.1 | 26.4 |
| Median | 30 | 10 | |
| Range | 0–80 | 0–90 | |
| mTOR (number of cases) | Negative | 5 | 6 |
| 1 (+) | 2 | 12 | |
| 2 (++) | 6 | 2 | |
| 3 (+++) | 12 | 5 | |
| 4EBP1 (% positive cells) | Mean | 42.8 | 82.8 |
| Median | 30 | 100 | |
| Range | 0–100 | 5–100 | |
| 4EBP1 (number of cases) | Negative | 3 | 0 |
| 1 (+) | 8 | 2 | |
| 2 (++) | 6 | 5 | |
| 3 (+++) | 8 | 18 | |
| S6RP (% positive cells) | Mean | 5.8 | 32 |
| Median | 0 | 20 | |
| Range | 0–70 | 0–100 | |
| S6RP (number of cases) | Negative | 19 | 5 |
| 1 (+) | 3 | 8 | |
| 2 (++) | 3 | 5 | |
| 3 (+++) | 0 | 6 | |