Biological evaluation of Syzygium guineense DC. against several cancer cell lines

NParts of the plantSolventsConcentrationType of cancerMajor findingReference
1Leaves, roots, barkMethanol, ethanol-Breast, colonStrong action against these cancer cells and colon cancer (CC) organoids was shown by the extract. Extraction effects on triple-negative breast cancer (TNBC) cell proliferation corresponded to suppression of the Wnt3a-induced catenin stabilization and transcriptional response[85]
2StemAqueous1,000 mg/kgLiver, colon, skin50% inhibition of growth (GI50) of 50 μg/mL was found to be an effective inhibitor of melanoma cell proliferation.[86]
3----Within the first day, the IC50 was 0.0008549 mg/mL. These plant extracts have antiproliferative capabilities that could be investigated[87]

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