Wound healing activity of FD

S/NMethodsSolventPlant partsConcentrationMajor findingsReference
1In vivoMethanolLeaves20, 40, 60, and 80%Methanolic extract of leaves at 20% concentration can heal wounds. The mice administered with an extract concentration of 80% exhibited the highest quantities of DNA and hydroxyl proline. The concentration of the extract influences how well it heals wounds[109]
2Scratch assaysHot aqueousLeavesLeaf extract can stimulate cell growth in a dose-dependent way. Compared to cells treated with ascorbic acid and untreated cells, F. deltoidea leaf extract accelerated wound closure in scratch assays[108]
3In vivoAqueousWhole plantsPlacebo containing 5% and 10%Wounds treated with F. deltoidea extract containing 5 or 10% of the total extract considerably expedited the healing process compared to wounds treated with sterile deionized water[107]
4Aqueous, methanol, and ethanolLeaves10–1,000 μg/mLInhibition of human liver glucuronidation activity was found in the range from 34.69 μg/mL to 398.10 μg/mL[110]
5In vivoHot aqueousLeavesThe liver and kidneys were unaffected by the extract. Rats treated with the extract gained weight, improved depressed behaviour, and had fewer pyknotic and dark-stained neurons in their hippocampus[111]