Characteristics of LGGs in the training and validation cohorts

CharacteristicsTraining datasetValidation datasetP
Age (year)42.54 ± 13.6643.64 ± 12.530.3570
KPS86.51 ± 12.2286.8 ± 13.870.4491
Gender0.7086
  Female175 (44.5%)61 (46.9%)
  Male218 (55.5%)69 (53.1%)
Histological_type0.9071
  Astrocytoma146 (49.7%)50 (51%)
  Oligodendroglioma148 (50.3%)48 (49%)
WHO_grade0.2414
  WHO grade 2197 (50.1%)57 (44.2%)
  WHO grade 3196 (49.9%)72 (55.8%)
Seizure_history0.6963
  Yes230 (62.2%)77 (64.7%)
  No140 (37.8%)42 (35.3%)
Sample_type0.5339
  Primary tumor381 (96.9%)128 (98.5%)
  Recurrent tumor12 (3.1%)2 (1.5%)
IDH_status0.1918
  Wildtype75 (19.9%)18 (14.2%)
  Mutant302 (80.1%)109 (85.8%)
Preoperative_antiseizure0.7701
  Yes201 (70%)63 (72.4%)
  No86 (30%)24 (27.6%)
Preoperative_corticosteroids0.7680
  Yes162 (57%)53 (59.6%)
  No122 (43%)36 (40.4%)
Headache_history0.4482
  Yes137 (38.2%)38 (33.6%)
  No222 (61.8%)75 (66.4%)
Motor_changes0.8413
  Yes84 (23.9%)29 (25.4%)
  No267 (76.1%)85 (74.6%)
Sensory_changes0.4837
  Yes65 (18.5%)17 (15%)
  No286 (81.5%)96 (85%)