From:  Virtual reality and mixed reality in the assessment of spatial memory

 Key factors influencing spatial memory

FactorImpact on spatial memory
Sex differencesSex-based strategy differences affect task performance depending on task demands and familiarity with the environment.
AgingAge-related declines primarily impact allocentric navigation, reducing efficiency in dynamic spatial tasks.
Neurological conditionsNeurological conditions disrupt hippocampal and entorhinal cortex function, affecting route learning and object-location memory.