Agreement in the identification of microcrystals for the senior observer in samples with crystals depending on the number of fields needed in the reference sample (disagreement shown in bold and underlined)
| Reference | DMSO+ | DMSO− | |||||
|---|---|---|---|---|---|---|---|
| Crystal negative | MSU | CPP | Crystal negative | MSU | CPP | ||
| 1–3 fields | MSU | 0 | 8 | 0 | 1 | 7 | 0 |
| CPP | 0 | 0 | 9 | 3 | 0 | 6 | |
| > 6 fields | CPP | 0 | 0 | 1 | 1 | 0 | 0 |
Agreement kappa: 1.00 for detection of crystals in DMSO+ simples; kappa: 0.62 for detection of crystals in DMSO− samples
FPR, ELB, FL, NS, TU, and JJMM: Conceptualization, Writing—review & editing. FPR and ELB: Data curation, Writing—original draft. FPR, ELB, FL, NS, TU, and JJMM read and approved the submitted version.
The authors declare that they have no conflicts of interest.
The study was included within a prospective inception gout cohort study approved by Cruces University Hospital Ethics and Clinical Investigation Committee (CEIC Cruces).
Written informed consent was obtained and signed by patients and investigators to use exceeds of biological samples, and approved by the CEIC Cruces.
Not applicable.
Data can be obtained by contacting Fernando Pérez-Ruiz (fernando.perezruiz@osakidetza.eus).
FPR was funded by a grant from Asociación de Reumatólogos de Cruces [04/2022]. The funders had no role in study design, data collection, and analysis, decision to publish, or preparation of the manuscript.
© The Author(s) 2023.