OSA consequences and their reversibility just by resolving OSA

Usually reversible (at least partially)Reversibility undeterminedUsually irreversible
Gout flares—immediately [43]Coronary [75]/peripheral [76, 77] artery diseaseResidual MSU with hyperuricemia [91, 92]
Atrial fibrillation—6 months [44]Dyslipidemia/atherosclerosis [78]Myocardial infarction [93]
Hypercoagulability—6 months [45, 46]Congestive heart failure [79]Ischemic stroke [94, 95]
Chronic kidney disease—3 months [4749]Autoimmune diseases [80, 81]Type 2 diabetes [96, 97]
Ventricular mechanical dysfunction—3 months [50]Chronic migraine [82]Cancer [98103]
Hypertension—6 months [5153]Hypothyroidism [83]Mitral valve disease [104]
Nonalcoholic fatty liver disease [54, 55]Systemic inflammation [84]Aortic valve stenosis [105]
Excessive daytime sleepiness [56]Erythrocytosis/polycythemia [85]Interstitial lung disease [106, 107]
Nocturia [57]Insomnia [86]-
Cognitive impairment—1 year [5860]Keratoconus [87]-
Depression—4 months [61, 62]Female infertility [88]-
Erectile dysfunction [6365]Glaucoma [89]-
Endothelial dysfunction—3 months [66]Inflammatory bowel disease [90]-
Gastroesophageal reflux [6771]--
Rate of Alzheimer’s disease progress [72]--
Telomere shortening—6 months [73, 74]--

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