From:  Horticultural therapy for the management of fibromyalgia: a narrative review

 Proposed effects of horticultural therapy in fibromyalgia management.

Proposed mechanismSupporting evidencePotential relevance to FM
Stress reductionReduced anxiety and improved mood [17, 31, 34]Chronic stress implicated in FM
Sensory stimulationExposure to multi-sensory stimuli [31]Relaxation and attentional distraction
Increased physical activityGardening and nature-based low-intensity movement activities [19, 20, 27]Improved conditioning and reduced kinesiophobia
Autonomic nervous system regulationIncreased parasympathetic activity and reduced physiological arousal [39, 40]FM associated with autonomic dysfunction
Neuroendocrine modulationReduced stress hormone activity [18, 38]May influence pain perception and fatigue
Neuroimmune regulationChanges in profile of inflammatory and immunologic biomarkers [4445]FM may involve neuroimmune dysregulation
Attention restoration and mindfulnessImproved mindfulness, affect, and emotional regulation [29, 30, 35, 36]May reduce pain catastrophizing and cognitive fatigue
Social engagement and self-efficacyImproved coping, competence, and self-efficacy [18]May improve functional capacity, adaptability, and participation in daily activities

FM: fibromyalgia.