From:  Horticultural therapy for the management of fibromyalgia: a narrative review

 Nature-based interventions in fibromyalgia.

StudyDesignPopulationInterventionMain outcomesKey findingsMajor limitations
Yavne et al., 2019 [28]Prospective cohortWomen with FMFloristry-based therapy programSF-36, FIQ, depression and anxiety measuresSignificant improvements in physical health, mental health, depression, anxiety, and FM-related symptomsNo control group; limited generalizability
López-Pousa et al., 2015 [29]Pilot interventionPatients with FMAerobic exercise in a mature forestPain, insomnia, well-beingReduced perceived pain and insomnia; improved well-beingSmall sample size; difficult to isolate effect of forest exposure from exercise
Gungormus et al., 2024 [30]RCTWomen with FMMultisensory nature-based stimulationPain intensity and pain thresholdReduced pain intensity and increased pain thresholdShort-term intervention
Serrat et al., 2023 [31]Pilot interventionPatients with FM and ME/CFSGuided forest bathing/hikingPain, anxiety, depression, insomnia, mood, mindfulnessImprovements across psychological and symptom domainsLimited sample size; lack of long-term follow-up
Serrat et al., 2020 (NAT-FM) [32]RCTPatients with FMMulticomponent intervention including education, exercise, psychological support, and nature exposurePhysical activity, kinesiophobia, coping, self-efficacy, emotional regulationImprovements in PROContribution of nature exposure cannot be determined

FIQ: fibromyalgia impact questionnaire; FM: fibromyalgia; ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; PRO: patient-reported outcomes; RCT: randomized controlled trial; SF-36: Short Form-36 Health Survey.