TY  - JOUR
TI  - The customization paradox: Why geometric precision is no substitute for biological integration?
AU  - Traub, Frank
AU  - Jung, Beatrice
AU  - Busse, Tilmann
AU  - Demir, Eren
AU  - Wunderlich, Felix
PY  - 2026
JO  - Exploration of BioMat-X
VL  - 3
SP  - 101360
DO  - 10.37349/ebmx.2026.101360
UR  - https://www.explorationpub.com/Journals/ebmx/Article/101360
AB  - Three-dimensional metal printing has made anatomical perfection readily achievable in orthopaedic reconstruction. Yet, as patient-specific implants transition from salvage solutions to routine applications, a critical question emerges: Does geometric precision improve long-term outcomes, or merely perfect existing problems? The article argues that customization defined by shape alone fails to address fundamental biological constraints, including stiffness mismatch, stress shielding, vascular compromise, and the inevitability of revision surgery. While additive manufacturing enables porous architectures and tailored mechanics, unchecked integration and over-conformity may jeopardize bone preservation and future surgical options. The article further highlights the professional and economic costs of patient-specific workflows and the limitations of static digital planning. True innovation, it is argued, lies not in achieving the “perfect fit,” but in designing implants that participate in bone biology and remain surgically defensible decades after implantation.
ER  -