@article{10.37349/ec.2026.101296,
abstract = {The Gerbode defect is characterized by a high ventricular septal defect associated with a defect in the septal leaflet of the tricuspid valve, allowing blood to enter the right atrium from the left ventricle. It accounts for approximately 0.08% of intracardiac shunts and may be congenital or acquired. We describe a rare case of Gerbode defect secondary to tricuspid valve endocarditis. A 58-year-old male patient presented with acute infective endocarditis due to Staphylococcus aureus, related to central venous access. Echocardiography showed a tricuspid valve with thickened leaflets and a small mobile image on the atrial side of the septal leaflet, as well as moderate to severe regurgitation. After completion of the antibiotic regimen with resolution of the infectious condition, the patient was discharged asymptomatic, and a new echocardiogram showed no vegetation on the tricuspid valve. During outpatient follow-up, he presented dyspnea on mild exertion, and consecutive echocardiograms showed moderate tricuspid insufficiency and significant pulmonary hypertension with a pulmonary artery systolic pressure of 83 mmHg (reference: 30 mmHg). He underwent right and left cardiac catheterization, which showed a Gerbode defect, and a transesophageal echocardiogram showed a shunt in the subaortic region measuring 6 to 8 mm, with a maximum gradient of 56 mmHg. He underwent elective surgery to correct the Gerbode defect and tricuspid valve repair, with a good clinical result. The Gerbode defect is rare, and the diagnosis can be challenging because it simulates other conditions. Treatment consists of closing the defect when it generates refractory symptoms or complications. The reported case was surgically corrected, with a good result and favorable evolution.},
author = {Ramos Barbosa, Roberto and Lott, Layla Pasolini and Batista, Layane Bonfante and Curcio de Paula Allemand, Anna Júlia and Eduardo Araújo Costa, Vinicius and Santos Guedes, Sergio Luís and Schreiber, Bárbara Keller and Barros, Lucas Crespo de and Sylvestre, Rodolfo Costa and Barbosa, Luiz Fernando Machado},
doi = {10.37349/ec.2026.101296},
journal = {Exploration of Cardiology},
elocation-id = {101296},
title = {Gerbode defect secondary to tricuspid valve endocarditis: a case report},
url = {https://www.explorationpub.com/Journals/ec/Article/101296},
volume = {4},
year = {2026}
}