@article{10.37349/eds.2025.100888,
abstract = {Over the last 60 years, only four new classes of antibiotics have been introduced, while the prevalence of antibiotic-resistant Gram-positive and Gram-negative bacteria has risen. This underscores the urgent need for new antibacterial therapeutics. This commentary leverages the recent exploration of γ-substituted-N-acylated-N-aminoethyl amino acid peptides (γ-AApeptides) to mimic the structures and function of natural antimicrobial peptides (AMPs), highlighting the promise and limitations for developing a new, effective treatment for antibiotic-resistant bacteria.},
author = {Fontaine, Jarais and Cai, Jianfeng},
doi = {10.37349/eds.2025.100888},
journal = {Exploration of Drug Science},
elocation-id = {100888},
title = {Recent exploration of γ-AApeptide based antimicrobial peptide mimics as potential therapeutics towards drug-resistant bacteria},
url = {https://www.explorationpub.com/Journals/eds/Article/100888},
volume = {3},
year = {2025}
}