TY  - JOUR
T1  - Multi-target and natural product-based multi-drug approach for anti-VEGF resistance in glioblastoma
AU  - Soumya, Sasikumar Jalajakumari
AU  - Arya, Kesavan Rathi
AU  - Abhinand, Chandran Sheela
AU  - Sunitha, Padmanabhan
AU  - Athira, Ajitha Prabhakaran
AU  - Nair, Achuthsankar Sukumaran
AU  - Oommen, Oommen V.
AU  - Sudhakaran, Perumana R.
Y1  - 2024///
JO  - Exploration of Drug Science
VL  - 2
IS  - 5
SP  - 567
EP  - 582
DO  - 10.37349/eds.2024.00062
UR  - https://www.explorationpub.com/Journals/eds/Article/100862
AB  - Glioblastoma (GBM) remains a formidable challenge in neuro-oncology due to its aggressive nature and propensity for therapeutic resistance. Anti-vascular endothelial growth factor (VEGF) therapies, although promising, often encounter resistance that limits their clinical efficacy. A multi-target and multi-drug approach has emerged as compelling strategies to address this resistance to enhance the treatment outcomes. This review examines the complex environment of anti-VEGF resistant GBM and analyses a multi-target therapeutic approach using natural products.
ER  -