TY  - JOUR
T1  - Reactivation of latent hepatitis B infection during immunosuppressive therapy with guselkumab for plaque psoriasis: a case report
AU  - Franchi, Elena
AU  - Costanzo, Arianna A. C.
AU  - Cursaro, Carmela
AU  - Lonardo, Amedeo
AU  - Lasagni, Claudia
AU  - Andreone, Pietro
Y1  - 2023///
JO  - Exploration of Drug Science
VL  - 1
IS  - 6
SP  - 468
EP  - 474
DO  - 10.37349/eds.2023.00031
UR  - https://www.explorationpub.com/Journals/eds/Article/100831
AB  - Reactivation of hepatitis B virus (HBV; RHBV) is a significant concern during immunosuppressive therapy, as it can lead to severe hepatitis and liver failure. The article reports a case of RHBV during treatment with guselkumab, an interleukin-23 inhibitor in a patient with inactive HBV infection and psoriasis. This report highlights the importance of screening for HBV prior to immunosuppressive therapy and initiating prophylactic therapy when necessary to prevent reactivation and its complications.
ER  -