@article{10.37349/edd.2025.100591,
abstract = {Aim: The current state of the problem of stomach and duodenal diseases presupposes a mandatory examination of patients for the presence of Helicobacter pylori infection. Highly specific and sensitive diagnostic methods are known and applied, however, the problem of removal from clinical laboratories, isolation, including during a pandemic, dictates the search for new solutions. Methods: Mobile diagnostic solutions based on portable devices with highly sensitive quartz piezoelectric sensors were investigated using a variety of devices (1–8 sensor elements) and data processing algorithms. Results: A three-year volunteer monitoring study demonstrated that sensor arrays are informative for exhaled air and volatile skin compound analysis, enabling both point diagnostics and long-term tracking. Conclusions: The study demonstrates the significant potential of sensor libraries in non-invasive diagnostics, particularly through the innovative application of facial skin projection for volatile marker detection. Three diagnostic approaches have been presented for assessing stomach and esophageal conditions via non-invasive monitoring of exhaled air composition and volatile skin compounds. The authors' extensive experience in breath urease testing for both adults and children enabled purposeful modifications of diagnostic devices and data processing algorithms. A three-year volunteer monitoring study during anti-Helicobacter therapy and dietary interventions revealed high stability and informativeness of the urease test utilizing chemical sensor arrays. Notably, this research represents the first demonstration of facial organ projection as a method for stomach condition assessment and volatile molecule monitoring without sample collection, showcasing promising prospects for future diagnostic applications.},
author = {Kuchmenko, Tatyana Anatolievna and Menzhulina, Daria and Umarkhanov, Ruslan and Kopaeva, Arina},
doi = {10.37349/edd.2025.100591},
journal = {Exploration of Digestive Diseases},
elocation-id = {100591},
title = {Novel research in the field of non-invasive diagnostics of Helicobacter pylori utilizing a library of chemical piezoelectric sensors and portable devices},
url = {https://www.explorationpub.com/Journals/edd/Article/100591},
volume = {4},
year = {2025}
}