TY  - JOUR
TI  - Amyloidosis and liver. Review.
AU  - Carrier, Paul
AU  - Debette-Gratien, Marilyne
AU  - Abraham, Julie
AU  - Cypierre, Anne
AU  - Cadranel, Jean-François
AU  - Jaccard, Arnaud
AU  - Loustaud-Ratti, Véronique
PY  - 2025
JO  - Exploration of Digestive Diseases
VL  - 4
SP  - 100589
DO  - 10.37349/edd.2025.100589
UR  - https://www.explorationpub.com/Journals/edd/Article/100589
AB  - Amyloidosis is a rare disease, corresponding to a deposition of proteins in various tissues. Amyloid light-chain (AL) amyloidosis can involve the liver in 17% to 45% of patients. Diagnosis of liver disease is based on specific criteria, coupling alkaline phosphatases and hepatomegaly. Liver stiffness is altered in cases of heart involvement, and overall, in cases of liver involvement. Liver biopsy is generally avoided due to an important bleeding risk. Treatment is essentially based on stem cell transplantation and chemotherapy, with large progress during the last decade. Liver involvement recovery is generally diagnosed with a reduction in alkaline phosphatases and in liver size.
ER  -