@article{10.37349/ent.2023.00052,
abstract = {Post-translational modifications (PTMs) of alpha-synuclein (α-syn) can alter protein aggregation propensity to affect α-syn oligomer and fibril formation. The inflammatory response in Parkinson’s disease (PD) is mediated by microglia, astrocytes, T cells, B cells, macrophages, and neutrophils, which respond to α-syn aggregates in an attempt to clear synucleinopathy and restore brain homeostasis. This review focuses on the effects of PTMs on α-syn aggregation and cell-specific immune responses to α-syn aggregates in the context of PD.},
author = {Khan, Zaina and Jung, Yoo Jin},
doi = {10.37349/ent.2023.00052},
journal = {Exploration of Neuroprotective Therapy},
pages = {281--298},
title = {{The effects of post-translational modifications on alpha-synuclein aggregation and immune cell activation in Parkinson’s disease}},
url = {https://www.explorationpub.com/Journals/ent/Article/100452},
volume = {3},
year = {2023},
number = {5}
}