@article{10.37349/ent.2025.1004106,
abstract = {Background: High-intensity training (HIT) increases walking speed for individuals with chronic stroke. Several recent studies have examined its application for those in the subacute phase following a stroke. This systematic review examines the application of HIT in the subacute phase following a stroke. Methods: A systematic search for studies that compared HIT (defined as 60–84% heart rate reserve or 77–93% heart rate maximum) to lower-intensity training, conventional physical therapy, placebo, or no intervention in adults 0–6 months post stroke. Randomized or quasi-randomized controlled trials, cohort studies, and case-controlled studies published in peer-reviewed journals in English were included. The primary outcome of interest was walking speed; the secondary outcome was walking endurance. Two independent evaluators performed literature selection, data extraction, and assessed study quality using the revised Cochrane risk-of-bias tool. Reporting followed PRISMA guidelines. Results: Of 1,642 studies initially retrieved, 10 studies with a total of 677 participants were included. All experimental groups showed an average positive change in self-selected walking speed (range: 0.20–0.56 m/s). HIT resulted in statistically significant improvements in walking speed versus comparison interventions in 4 studies. Eight studies that measured walking endurance found an average increase of 60 to 197 m following HIT. Discussion: HIT demonstrated superior outcomes in self-selected walking speed and walking endurance for individuals in the subacute phase post stroke, both immediately following intervention and at follow-up. These findings align with the clinical practice guideline (CPG) for chronic stroke patients. Further randomized clinical trials are needed to strengthen the evidence.},
author = {Ojeda-Manzano, Alejandro and Pérez-Padilla, Elsy Arlene and Sanguino-Suárez, Sergio Iván and Cabelka, Christine and Salgado, Humberto and Borstad, Alexandra},
doi = {10.37349/ent.2025.1004106},
journal = {Exploration of Neuroprotective Therapy},
elocation-id = {1004106},
title = {The effects of high-intensity training on walking speed and endurance in the subacute phase poststroke: a systematic review},
url = {https://www.explorationpub.com/Journals/ent/Article/1004106},
volume = {5},
year = {2025}
}