TY - JOUR T1 - SARS-CoV-2: overview of immune response, insights into vaccine platforms and their challenges AU - Omar, Balram Ji AU - Singh, Arpana AU - Singh, Vanya AU - Kothari, Ashish AU - Pai, Manju O. Y1 - 2022/// JO - Exploration of Immunology VL - 2 IS - 3 SP - 245 EP - 263 DO - 10.37349/ei.2022.00049 UR - https://www.explorationpub.com/Journals/ei/Article/100349 AB - The crown-like shaped viruses known as coronaviruses which were first reported in the 1960’s have caused three epidemics in the past two decades namely, coronavirus disease-19 (COVID-19), severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). SARS coronavirus 2 (SARS-CoV-2) was first reported in the latter half of December in Wuhan, a city of China, with people affected by deadly pneumonia with unknown etiology. Since then, the world has experienced two phases of virus spread with different symptoms and disease severity. This review embarks on the journey to investigate candidate molecules of this virus which can and are being investigated for various vaccine formulations and to discuss immunity developed against this virus. ER -