TY - JOUR T1 - Primary biliary cholangitis, a rising health burden AU - Elnaggar, Mohamed Bassyouny Aboueleinin AU - Elkhattib, Ismail AU - Abomhya, Ahmed Abdelsatar Ali AU - Boyer, James Lorenzen Y1 - 2024/// JO - Exploration of Immunology VL - 4 IS - 5 SP - 658 EP - 678 DO - 10.37349/ei.2024.00165 UR - https://www.explorationpub.com/Journals/ei/Article/1003165 AB - Primary biliary cholangitis (PBC) is a rare immune-mediated disease, commonly affecting women in their 40s, and ultimately progressing to liver failure. The incidence and prevalence of the disease are increasing worldwide, possibly due to better diagnostic tools. This review will focus on its epidemiology, pathophysiology, diagnosis, prognosis, and new developments in therapy. ER -