TY  - JOUR
T1  - The role of complement component C1q in angiogenesis
AU  - Spazzapan, Mariagiulia
AU  - Pegoraro, Silvia
AU  - Agostinis, Chiara
AU  - Bulla, Roberta
Y1  - 2023///
JO  - Exploration of Immunology
VL  - 3
IS  - 6
SP  - 574
EP  - 589
DO  - 10.37349/ei.2023.00122
UR  - https://www.explorationpub.com/Journals/ei/Article/1003122
AB  - The complement component C1q plays a role as a pro-angiogenic factor in different contexts, acting in a complement-independent way. For example, this molecule is able to foster the remodeling of the spiral arteries for a physiological pregnancy and to promote the wound healing process. It is also involved in angiogenesis after post-stroke ischemia. Furthermore, it has a role in supporting the tumor vessel growth. Given its role in promoting angiogenesis both under physiological and pathological situations, other studies are needed to understand its potential therapeutic implications.
ER  -