TY  - JOUR
T1  - Clinical aspect, pathogenesis and therapy options of alopecia induced by hormonal therapy for breast cancer
A1  - Rossi, Alfredo
A1  - Caro, Gemma
A1  - Magri, Francesca
A1  - Fortuna, Maria Caterina
A1  - Carlesimo, Marta
Y1  - 2021///
KW  - Alopecia
KW  - hormonal therapy
KW  - breast cancer
JF  - Exploration of Targeted Anti-tumor Therapy
VL  - 2
IS  - 5
SP  - 490
EP  - 495
DO  - 10.37349/etat.2021.00059
UR  - https://www.explorationpub.com/Journals/etat/Article/100260
N2  - Adjuvant hormonal therapy is one of the most important treatments of hormone-receptor-positive breast cancer and includes selective estrogen receptor modulators, aromatase inhibitors, and luteinizing hormone-releasing hormone analogs. In patients receiving these drugs, a progressive recession of frontal-temporal hairlines is often observed, such as a certain grade of hair miniaturization in the same areas and the central scalp area, producing a pseudo-female androgenic alopecia, which has to be considered oncotherapy-induced alopecia. The aim of this work, is to describe the clinical aspects and pathogenesis of this type of alopecia and to analyze the different drugs which have been proposed until now. The authors concude that topical hormones should not be considered as a therapeutic approach because of their direct or indirect oncogenic potential. A therapeutic approach that could be both safe and effective is proposed.
ER  -