TY  - JOUR
T1  - A case report: 19-year-old male diagnosed with C1q nephropathy requiring renal replacement therapy
AU  - Choueiri, Randa
AU  - Faddoul, Joelle
AU  - Ghorra, Claude
AU  - Najjar, Jaqueline Al
AU  - Akiki, Beatrice-Blondine
AU  - Boustany, Sora
AU  - Nseir, Vanessa
Y1  - 2022///
JO  - Exploration of Medicine
VL  - 3
IS  - 4
SP  - 386
EP  - 392
DO  - 10.37349/emed.2022.00101
UR  - https://www.explorationpub.com/Journals/em/Article/1001101
AB  - C1q nephropathy is a rare glomerular disease. Clinical presentation is diverse and ranges from asymptomatic hematuria or proteinuria to symptoms and signs of nephrotic/nephritic syndrome. On light microscopy, it can be classified into two subtypes: minimal change disease (MCD)/focal segmental glomerulosclerosis (FSGS) group and immune complex mediated proliferative glomerulonephritis group. A case of a 19-year-old male patient presenting nausea and decreased appetite will be reported. The labs showed severe nephrotic syndrome and a progressive kidney injury over a few months that were never diagnosed. The immune workup came back negative. The patient mentioned that he was taking protein shakes a few months earlier for bettering his physical fitness. A renal biopsy was done and showed a major reduction in renal mass and C1q nephropathy. He received steroids without any improvement. He was started on hemodialysis afterward then got transplanted 8 months later. In front of this rapid deterioration, FSGS might be the underlying etiology rather than MCD. Further studies are warranted to establish a connection between protein supplements, and progression of kidney disease.
ER  -