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    [0] => Array
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            [ArticleId] => 389
            [Create_Time] => 2022-09-22
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            [JournalsId] => 12
            [Title] => Exploration of Foods and Foodomics: a new adventure
            [Abstract] => 
            [AbstractComplete] => 
            [Names] => Alejandro Cifuentes, Elena Ibáñez
            [Doi] => 10.37349/eff.2022.00001
            [Published] => March 01, 2023
            [Viewed] => 864
            [Downloaded] => 89
            [Subject] => Editorial
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2022.00001
            [Inline] => 1
            [Type] => 1
            [Issue] => 1
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:1–4
            [Recommend] => 0
            [Keywords] => 
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10101
            [ris] => https://www.explorationpub.com/uploads/Article/A10101/55f9eb49c88ed0f8f5e121cff0bf1362.ris
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            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Cifuentes A, Ibáñez E. Exploration of Foods and Foodomics: a new adventure. Explor Foods Foodomics. 2023;1:1–4. <a href="https://doi.org/10.37349/eff.2022.00001">https://doi.org/10.37349/eff.2022.00001</a>
            [Jindex] => 0
            [CName] => AlejandroCifuentes,ElenaIb&#x000E1;&#x000F1;ez,
            [CEmail] => a.cifuentes@csic.es,elena.ibanez@csic.es,
            [Ris_Time] => 2022-09-21 02:51:09
            [Bib_Time] => 2022-09-21 02:51:09
            [KeysWordContens] => Exploration of Foods and Foodomics: a new adventure,,,Alejandro Cifuentes, Elena Ibáñez
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 36
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    [1] => Array
        (
            [ArticleId] => 562
            [Create_Time] => 2023-04-26
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202305/20230511022604.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10102/10102.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10102/10102.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10102/10102_cover.png
            [JournalsId] => 12
            [Title] => Phytochemical screening of <em>Psidium guajava</em> and <em>Carica papaya</em> leaves aqueous extracts cultivated in Greece and their potential as health boosters
            [Abstract] => Aim:
The scope of the present study was to investigate the phytochemical profile of <i>Psidium guajava</i> and <i>Carica papaya</i> leaves aqueous extracts, from plants cultivated on Crete island in Greece.


            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>The scope of the present study was to investigate the phytochemical profile of <em>Psidium guajava</em> and <em>Carica papaya </em>leaves aqueous extracts, from plants cultivated on Crete island in Greece.</p>
</div>
<div>
<h3>Methods:</h3>
<p>Total phenolic content (TPC) in the aqueous extracts was determined spectrometrically using the Folin-Ciocalteu (F-C) assay. The identification and quantification of different phenolic compounds in the aqueous extracts were conducted using reversed-phase high-performance liquid chromatography (RP-HPLC) analysis. Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion using inductively coupled plasma mass spectrometry (ICP-MS) method.</p>
</div>
<div>
<h3>Results:</h3>
<p>TPC in the aqueous extracts was found to be 28.0 g gallic acid equivalent (GAE)/kg dry leaves for <em>Psidium guajava</em> leaves aqueous extract and 15.0 g GAE/kg dry leaves for <em>Carica papaya</em> leaves aqueous extract. The dominant phenolic compounds in <em>Psidium guajava</em> leaves aqueous extract were myricetin (3,852 mg/kg dry sample) and rutin (670 mg/kg dry sample) while the dominant phenolic compounds in <em>Carica papaya</em> leaves aqueous extract were salicylic acid (338 mg/kg dry sample) and rutin (264 mg/kg dry sample). Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion, and it was found that no toxic metals were extracted whereas some nutritional benefits were achieved.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>Results proved that <em>Psidium guajava </em>and <em>Carica papaya </em>can be provided a strong antioxidant activity and can be used as medicinal plants.</p>
</div>

            [Names] => Dimitrios D. Ntakoulas ... Charalampos Proestos
            [Doi] => 10.37349/eff.2023.00002
            [Published] => April 26, 2023
            [Viewed] => 401
            [Downloaded] => 15
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00002
            [Inline] => 1
            [Type] => 1
            [Issue] => 1
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:5–14
            [Recommend] => 0
            [Keywords] =>  
<em>Psidium guajava</em> leaves, 
<em>Carica papaya </em>leaves, phytochemical profile, phenolic compounds, health claims, elemental content
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10102
            [ris] => https://www.explorationpub.com/uploads/Article/A10102/04d93eb0af8155959c245f343825f572.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10102/c44546962fa9cbd00957c8a7f828b953.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Ntakoulas DD, Pasias IN, Raptopoulou KG, Dimitriou G, Proestos C. Phytochemical screening of <i>Psidium guajava</i> and <i>Carica papaya</i> leaves aqueous extracts cultivated in Greece and their potential as health boosters. Explor Foods Foodomics. 2023;1:5–14. <a href="https://doi.org/10.37349/eff.2023.00002">https://doi.org/10.37349/eff.2023.00002</a>
            [Jindex] => 0
            [CName] => CharalamposProestos,
            [CEmail] => harpro@chem.uoa.gr,
            [Ris_Time] => 2023-04-25 08:06:00
            [Bib_Time] => 2023-04-25 08:06:00
            [KeysWordContens] => Phytochemical screening of Psidium guajava and Carica papaya leaves aqueous extracts cultivated in Greece and their potential as health boosters, 
Psidium guajava leaves, 
Carica papaya leaves, phytochemical profile, phenolic compounds, health claims, elemental content,

Aim:
The scope of the present study was to investigate the phytochemical profile of Psidium guajava and Carica papaya leaves aqueous extracts, from plants cultivated on Crete island in Greece.


Methods:
Total phenolic content (TPC) in the aqueous extracts was determined spectrometrically using the Folin-Ciocalteu (F-C) assay. The identification and quantification of different phenolic compounds in the aqueous extracts were conducted using reversed-phase high-performance liquid chromatography (RP-HPLC) analysis. Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion using inductively coupled plasma mass spectrometry (ICP-MS) method.


Results:
TPC in the aqueous extracts was found to be 28.0 g gallic acid equivalent (GAE)/kg dry leaves for Psidium guajava leaves aqueous extract and 15.0 g GAE/kg dry leaves for Carica papaya leaves aqueous extract. The dominant phenolic compounds in Psidium guajava leaves aqueous extract were myricetin (3,852 mg/kg dry sample) and rutin (670 mg/kg dry sample) while the dominant phenolic compounds in Carica papaya leaves aqueous extract were salicylic acid (338 mg/kg dry sample) and rutin (264 mg/kg dry sample). Different metals were also determined (K, Fe, Zn, Ca, Mg, Pb, and Cd) to investigate the potential health claims or hazards in the water extractable infusion, and it was found that no toxic metals were extracted whereas some nutritional benefits were achieved.


Conclusions:
Results proved that Psidium guajava and Carica papaya can be provided a strong antioxidant activity and can be used as medicinal plants.

,Dimitrios D. Ntakoulas ... Charalampos Proestos
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 38
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            [ArticleId] => 563
            [Create_Time] => 2023-04-27
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202304/20230427052158.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10103/10103.xml
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            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10103/10103_cover.png
            [JournalsId] => 12
            [Title] => Atlantic algae as food and their extracts
            [Abstract] => Among the species of the rich algological flora of the North Atlantic, some can be used for direct consumption in human food, although few are currently cultivated on a large scale and/or marketed f
            [AbstractComplete] => 
<p>Among the species of the rich algological flora of the North Atlantic, some can be used for direct consumption in human food, although few are currently cultivated on a large scale and/or marketed for this purpose. The European tradition regarding this custom is practically nil and the expression of current eating habits is little different from the past. In Europe, only in times of hunger (for example, during the Great World Wars) was seaweed consumed by the populations closest to the coastline. In addition to the multiple applications described, which expanded enormously in the 1970s, based on phycocolloids (agar, carrageenans, and alginates)&#x2014;used as thickeners in the food industry, in soups, meat preserves, dairy products, and pastries&#x2014;there is currently a trend of increasing consumption, both in North America and Europe.</p>

            [Names] => Leonel Pereira
            [Doi] => 10.37349/eff.2023.00003
            [Published] => April 27, 2023
            [Viewed] => 763
            [Downloaded] => 29
            [Subject] => Review
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00003
            [Inline] => 1
            [Type] => 1
            [Issue] => 1
            [Topic] => 133
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:15–31
            [Recommend] => 0
            [Keywords] =>  Macroalgae, Atlantic seaweeds, novel food, nutritional composition, polysaccharides, phycocolloids, sea vegetables, vitamins
            [DetailTitle] => The food (r)evolution towards food quality/security and human nutrition
            [DetailUrl] => https://www.explorationpub.com/Journals/eff/Special_Issues/133
            [Id] => 10103
            [ris] => https://www.explorationpub.com/uploads/Article/A10103/89078ac11279eb1d94cab8f942634cef.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10103/cb4efb726cdf56720f3d433872d0e9e4.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Pereira L. Atlantic algae as food and their extracts. Explor Foods Foodomics. 2023;1:15–31. <a href="https://doi.org/10.37349/eff.2023.00003">https://doi.org/10.37349/eff.2023.00003</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-04-25 08:27:53
            [Bib_Time] => 2023-04-25 08:27:53
            [KeysWordContens] => Atlantic algae as food and their extracts, Macroalgae, Atlantic seaweeds, novel food, nutritional composition, polysaccharides, phycocolloids, sea vegetables, vitamins,
Among the species of the rich algological flora of the North Atlantic, some can be used for direct consumption in human food, although few are currently cultivated on a large scale and/or marketed for this purpose. The European tradition regarding this custom is practically nil and the expression of current eating habits is little different from the past. In Europe, only in times of hunger (for example, during the Great World Wars) was seaweed consumed by the populations closest to the coastline. In addition to the multiple applications described, which expanded enormously in the 1970s, based on phycocolloids (agar, carrageenans, and alginates)—used as thickeners in the food industry, in soups, meat preserves, dairy products, and pastries—there is currently a trend of increasing consumption, both in North America and Europe.
,Leonel Pereira
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 45
        )

    [3] => Array
        (
            [ArticleId] => 564
            [Create_Time] => 2023-04-27
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202304/20230426024127.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10104/10104.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10104/10104.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10104/10104_cover.png
            [JournalsId] => 12
            [Title] => Green subcritical water extraction of <em>Mentha x rotundifolia</em> leaves collected in different annuities
            [Abstract] => Aim:
In this work, the development for the first time of a green and efficient method to obtain bioactive extracts from <i>Mentha x rotundifolia</i> leaves has been investigated.


Methods:
The effi
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>In this work, the development for the first time of a green and efficient method to obtain bioactive extracts from <em>Mentha x rotundifolia </em>leaves has been investigated.</p>
</div>
<div>
<h3>Methods:</h3>
<p>The efficiency of three techniques [microwave-assisted extraction (MAE), subcritical water extraction (SWE), and ultrasound-assisted extraction (UAE)] was compared in terms of total phenolic content (TPC) and antioxidant activity [1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzthioazoline-6-sulfonic acid) (ABTS) assays].</p>
</div>
<div>
<h3>Results:</h3>
<p>Under similar operating conditions, SWE outperformed MAE and UAE for providing <em>M. rotundifolia</em> extracts with improved antioxidant activity. Further in-depth optimization of the SWE method by means of a Box-Behnken experimental design showed 120°C, 5 min, 0.08 g dry sample: 1 mL water and 2 extraction cycles as optimal experimental parameters to provide the maximum yield of phenolics and the highest bioactivity. The application of the developed SWE method to <em>M. rotundifolia</em> leaves collected in different annuities (2014–2017) showed, in general, no significant differences regarding both composition and antioxidant capacity, as expected from plant samples grown in field under drip irrigation conditions.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>The SWE method here optimized is shown as a sustainable and efficient alternative for providing bioactive <em>M. rotundifolia</em> extracts with application as functional ingredients, natural preservatives, etc. in the food industry, among others.</p>
</div>

            [Names] => María Jesús García-Sarrió ... María Luz Sanz
            [Doi] => 10.37349/eff.2023.00004
            [Published] => April 27, 2023
            [Viewed] => 252
            [Downloaded] => 16
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00004
            [Inline] => 1
            [Type] => 1
            [Issue] => 1
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:32–42
            [Recommend] => 0
            [Keywords] =>  
<em>Mentha x rotundifolia</em>
, microwave-assisted extraction, subcritical water extraction, ultrasound-assisted extraction, phenolic compounds, antioxidant activity, liquid chromatography-mass spectrometry
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10104
            [ris] => https://www.explorationpub.com/uploads/Article/A10104/2c8b4b06f93949595713ea131665ad77.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10104/73898167d0c81fb3a175f017f6e42d06.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => García-Sarrió MJ, Soria AC, Galindo-Iranzo P, Sanz ML. Green subcritical water extraction of <i>Mentha x rotundifolia</i> 
leaves collected in different annuities. Explor Foods Foodomics. 2023;1:32–42. <a href="https://doi.org/10.37349/eff.2023.00004">https://doi.org/eff.2023.00004</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-04-26 06:25:01
            [Bib_Time] => 2023-04-26 06:25:01
            [KeysWordContens] => Green subcritical water extraction of Mentha x rotundifolia leaves collected in different annuities, 
Mentha x rotundifolia
, microwave-assisted extraction, subcritical water extraction, ultrasound-assisted extraction, phenolic compounds, antioxidant activity, liquid chromatography-mass spectrometry,

Aim:
In this work, the development for the first time of a green and efficient method to obtain bioactive extracts from Mentha x rotundifolia leaves has been investigated.


Methods:
The efficiency of three techniques [microwave-assisted extraction (MAE), subcritical water extraction (SWE), and ultrasound-assisted extraction (UAE)] was compared in terms of total phenolic content (TPC) and antioxidant activity [1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzthioazoline-6-sulfonic acid) (ABTS) assays].


Results:
Under similar operating conditions, SWE outperformed MAE and UAE for providing M. rotundifolia extracts with improved antioxidant activity. Further in-depth optimization of the SWE method by means of a Box-Behnken experimental design showed 120°C, 5 min, 0.08 g dry sample: 1 mL water and 2 extraction cycles as optimal experimental parameters to provide the maximum yield of phenolics and the highest bioactivity. The application of the developed SWE method to M. rotundifolia leaves collected in different annuities (2014–2017) showed, in general, no significant differences regarding both composition and antioxidant capacity, as expected from plant samples grown in field under drip irrigation conditions.


Conclusions:
The SWE method here optimized is shown as a sustainable and efficient alternative for providing bioactive M. rotundifolia extracts with application as functional ingredients, natural preservatives, etc. in the food industry, among others.

,María Jesús García-Sarrió ... María Luz Sanz
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 55
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    [4] => Array
        (
            [ArticleId] => 578
            [Create_Time] => 2023-04-28
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202304/20230427084507.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10105/10105.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10105/10105.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10105/10105_cover.png
            [JournalsId] => 12
            [Title] => Monitoring nanomaterials in food: a critical overview, perspectives, and challenges
            [Abstract] => Nanoscience and nanotechnology have experienced a dizzying development in recent years, which undoubtedly contributes to various fields of human activity such as biotechnology, engineering, medical 
            [AbstractComplete] => 
<p>Nanoscience and nanotechnology have experienced a dizzying development in recent years, which undoubtedly contributes to various fields of human activity such as biotechnology, engineering, medical sciences, food security, etc. This impact has taken place in the food field too, especially in the role played by nanomaterials (NMs) for producing quality nano-based products, food shelf life, and target-specific bioactive delivery, since traditionally the presence of these materials was not at the nano-scale. Anyway, switching these materials to their nano-forms carries benefits as well as risks that must be assessed. Thus, the evaluation of the presence and quantity of these NMs must be achieved based on reliable physic-chemical-analytical information; hence the impact that analytical chemistry should have in the nanoscience to develop validated methodologies for its control. Currently, this fact represents a significant challenge due to the difficulties of measuring entities at the nanoscale in complex samples such as those of food. This review critically explores these analytical challenges, their difficulties, and their trends within the general framework of NMs’ analytical monitoring in food.</p>

            [Names] => Natalia Villamayor ... Ángel Ríos
            [Doi] => 10.37349/eff.2023.00005
            [Published] => April 27, 2023
            [Viewed] => 383
            [Downloaded] => 43
            [Subject] => Review
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00005
            [Inline] => 1
            [Type] => 1
            [Issue] => 1
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:43–61
            [Recommend] => 0
            [Keywords] =>  Nanomaterials, food, characterization, analytical nanometrology, size-based separation techniques, surface enhanced spectroscopies
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10105
            [ris] => https://www.explorationpub.com/uploads/Article/A10105/c8c19668568cd3706b4435d4809699ca.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10105/b6141deeb3d746ddcb4f40efb8749275.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Villamayor N, Villaseñor MJ, Ríos Á. Monitoring nanomaterials in food: a critical overview, perspectives, and challenges. Explor Foods Foodomics. 2023;1:43–61. <a href="https://doi.org/10.37349/eff.2023.00005">https://doi.org/10.37349/eff.2023.00005</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-04-27 01:21:40
            [Bib_Time] => 2023-04-27 01:21:40
            [KeysWordContens] => Monitoring nanomaterials in food: a critical overview, perspectives, and challenges, Nanomaterials, food, characterization, analytical nanometrology, size-based separation techniques, surface enhanced spectroscopies,
Nanoscience and nanotechnology have experienced a dizzying development in recent years, which undoubtedly contributes to various fields of human activity such as biotechnology, engineering, medical sciences, food security, etc. This impact has taken place in the food field too, especially in the role played by nanomaterials (NMs) for producing quality nano-based products, food shelf life, and target-specific bioactive delivery, since traditionally the presence of these materials was not at the nano-scale. Anyway, switching these materials to their nano-forms carries benefits as well as risks that must be assessed. Thus, the evaluation of the presence and quantity of these NMs must be achieved based on reliable physic-chemical-analytical information; hence the impact that analytical chemistry should have in the nanoscience to develop validated methodologies for its control. Currently, this fact represents a significant challenge due to the difficulties of measuring entities at the nanoscale in complex samples such as those of food. This review critically explores these analytical challenges, their difficulties, and their trends within the general framework of NMs’ analytical monitoring in food.
,Natalia Villamayor ... Ángel Ríos
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 45
        )

    [5] => Array
        (
            [ArticleId] => 597
            [Create_Time] => 2023-06-08
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202306/20230629034711.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10106/10106.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10106/10106.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10106/10106_cover.png
            [JournalsId] => 12
            [Title] => Correlation distance of browning characteristic and polyphenol distribution in apple slices from 20 Chinese cultivars
            [Abstract] => 
Aim:
The aim of this study is to investigate the polyphenol composition and distribution in the core, flesh, and peel of 20 apple varieties from China and its relation with browning characteristi
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>The aim of this study is to investigate the polyphenol composition and distribution in the core, flesh, and peel of 20 apple varieties from China and its relation with browning characteristics of apple slices in the drying process.</p>
</div>
<div>
<h3>Methods:</h3>
<p>In this paper, the prominent phenolic compounds, which was determined by photo diode array-high-performance liquid chromatography (PDA-HPLC), and the chromatic value [coherent infrared energy (CIE) L*, a*, b*] were correlation analysised.</p>
</div>
<div>
<h3>Results:</h3>
<p>The results showed that apple core, flesh, and peel were characterized by phloridzin, chlorogenic acid, quercetin, and related derivatives respectively. The 20 apple varieties showed a significant difference (<sup>* </sup><em>P</em> &lt; 0.05) in browning variation in the drying process. The browning at the initial stage was mainly L* declined, which was induced by polyphenols enzymatic oxidation. While the browning was characterized by b* and a* value increment at the end of the drying process, where the Maillard reaction was the dominant factor.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>The correlation distance between the main phenolic compounds in apple core, flesh, and peel with the average chromatic L*, a*, and b* values varied at different stages of the drying process.</p>
</div>

            [Names] => Wenyue Wang ... Jinfeng Bi
            [Doi] => 10.37349/eff.2023.00006
            [Published] => June 08, 2023
            [Viewed] => 287
            [Downloaded] => 28
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00006
            [Inline] => 1
            [Type] => 1
            [Issue] => 2
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:62–71
            [Recommend] => 0
            [Keywords] =>  Apple, polyphenols distribution, drying process, browning, correlation distance
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10106
            [ris] => https://www.explorationpub.com/uploads/Article/A10106/36a4d69c55a53b5e305e23b43de08a24.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10106/57cd43e5fa66242c7cd03628f1530a82.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Wang W, Li X, Hu J, Bi J. Correlation distance of browning characteristic and polyphenol distribution in apple slices from 20 Chinese cultivars. Explor Foods Foodomics. 2023;1:62–71. <a href="https://doi.org/10.37349/eff.2023.00006">https://doi.org/10.37349/eff.2023.00006</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-05-31 03:07:02
            [Bib_Time] => 2023-05-31 03:07:02
            [KeysWordContens] => Correlation distance of browning characteristic and polyphenol distribution in apple slices from 20 Chinese cultivars, Apple, polyphenols distribution, drying process, browning, correlation distance,

Aim:
The aim of this study is to investigate the polyphenol composition and distribution in the core, flesh, and peel of 20 apple varieties from China and its relation with browning characteristics of apple slices in the drying process.


Methods:
In this paper, the prominent phenolic compounds, which was determined by photo diode array-high-performance liquid chromatography (PDA-HPLC), and the chromatic value [coherent infrared energy (CIE) L*, a*, b*] were correlation analysised.


Results:
The results showed that apple core, flesh, and peel were characterized by phloridzin, chlorogenic acid, quercetin, and related derivatives respectively. The 20 apple varieties showed a significant difference (* P < 0.05) in browning variation in the drying process. The browning at the initial stage was mainly L* declined, which was induced by polyphenols enzymatic oxidation. While the browning was characterized by b* and a* value increment at the end of the drying process, where the Maillard reaction was the dominant factor.


Conclusions:
The correlation distance between the main phenolic compounds in apple core, flesh, and peel with the average chromatic L*, a*, and b* values varied at different stages of the drying process.

,Wenyue Wang ... Jinfeng Bi
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 57
        )

    [6] => Array
        (
            [ArticleId] => 644
            [Create_Time] => 2023-07-01
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202307/20230704081026.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10107/10107.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10107/10107.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10107/10107_cover.png
            [JournalsId] => 12
            [Title] => Untargeted and quantitative analyses of amine and phenol compounds in Baijiu via chemical isotope labeling
            [Abstract] => 
Aim:
The aim of this study is to comprehensively investigate the distribution of amine and phenol compounds in different flavors of Baijiu.


Methods:

12C-/13C-dansyl chloride labeling was 
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>The aim of this study is to comprehensively investigate the distribution of amine and phenol compounds in different flavors of Baijiu.</p>
</div>
<div>
<h3>Methods:</h3>
<p>
<sup>12</sup>C-/<sup>13</sup>C-dansyl chloride labeling was applied for untargeted and quantitative analyses of amine and phenol compounds in Baijiu.</p>
</div>
<div>
<h3>Results:</h3>
<p>A total of 267 amine/phenol compounds were detected, and 30 of them were confirmed by the standards. 4 of 30 confirmed compounds were newly identified in Baijiu, and 16 ones were related with flavor or biological activity. After statistical analysis, 34 amine/phenol compounds were defined as potential markers for indicating sauce flavor, strong flavor, and light flavor Baijiu. 30 compounds in Baijiu were quantified with high precision, high accuracy, and high sensitivity. Results of the untargeted and quantitative analyses indicated that the number and contents of amine and phenol compounds were generally richest in sauce flavor Baijiu, while lowest in light flavor Baijiu.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>The results obtained in the research are beneficial for comprehensively understanding the amine and phenol compounds in Baijiu and further provide the basis for the flavor blending of Baijiu.</p>
</div>

            [Names] => Xiaoyu Xie ... Guowang Xu
            [Doi] => 10.37349/eff.2023.00007
            [Published] => June 30, 2023
            [Viewed] => 329
            [Downloaded] => 53
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00007
            [Inline] => 1
            [Type] => 1
            [Issue] => 2
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:72–82
            [Recommend] => 1
            [Keywords] =>  Amine/phenol compounds, Baijiu, chemical isotope labeling, liquid chromatography, mass spectrometry
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10107
            [ris] => https://www.explorationpub.com/uploads/Article/A10107/9e2ce154d1c675ceebb61ec75c34a1c0.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10107/59b8a6746f20d8ca7c5375e2ca5f7450.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Xie X, Zheng F, Chen T, Liu X, Hu C, Ma M, et al. Untargeted and quantitative analyses of amine and phenol
compounds in Baijiu via chemical isotope labeling. Explor Foods Foodomics. 2023;1:72–82. <a href="https://doi.org/10.37349/eff.2023.00007">https://doi.org/10.37349/eff.2023.00007</a>
            [Jindex] => 0
            [CName] => XinLu,
            [CEmail] => luxin722@dicp.ac.cn,
            [Ris_Time] => 2023-06-30 03:07:46
            [Bib_Time] => 2023-06-30 03:07:46
            [KeysWordContens] => Untargeted and quantitative analyses of amine and phenol compounds in Baijiu via chemical isotope labeling, Amine/phenol compounds, Baijiu, chemical isotope labeling, liquid chromatography, mass spectrometry,

Aim:
The aim of this study is to comprehensively investigate the distribution of amine and phenol compounds in different flavors of Baijiu.


Methods:

12C-/13C-dansyl chloride labeling was applied for untargeted and quantitative analyses of amine and phenol compounds in Baijiu.


Results:
A total of 267 amine/phenol compounds were detected, and 30 of them were confirmed by the standards. 4 of 30 confirmed compounds were newly identified in Baijiu, and 16 ones were related with flavor or biological activity. After statistical analysis, 34 amine/phenol compounds were defined as potential markers for indicating sauce flavor, strong flavor, and light flavor Baijiu. 30 compounds in Baijiu were quantified with high precision, high accuracy, and high sensitivity. Results of the untargeted and quantitative analyses indicated that the number and contents of amine and phenol compounds were generally richest in sauce flavor Baijiu, while lowest in light flavor Baijiu.


Conclusions:
The results obtained in the research are beneficial for comprehensively understanding the amine and phenol compounds in Baijiu and further provide the basis for the flavor blending of Baijiu.

,Xiaoyu Xie ... Guowang Xu
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 56
        )

    [7] => Array
        (
            [ArticleId] => 646
            [Create_Time] => 2023-07-01
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202306/20230630180525.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10108/10108.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10108/10108.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10108/10108_cover.png
            [JournalsId] => 12
            [Title] => Untargeted lipidomics for evaluating fish authenticity: the case of wild-caught and farmed species of <em>Sparus aurata</em>
            [Abstract] => Aim:
This study aims to develop sensitive and reliable analytical technologies to enable the distinction between wild-caught and farmed fish through appropriate molecular markers to protect consu
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>This study aims to develop sensitive and reliable analytical technologies to enable the distinction between wild-caught and farmed fish through appropriate molecular markers to protect consumers from fraudulent fish labelling. Gilthead sea bream, <em>Sparus aurata </em>L. (<em>S. aurata </em>L.), is a very common fish used as foodstuff worldwide and globally produced in aquaculture in the Mediterranean basin. Wild-caught and farmed species are very different in feed and lifestyle and the quality and safety of these products strongly depend on fish growth, processing history, and storage conditions.</p>
</div>
<div>
<h3>Methods:</h3>
<p>Hydrophilic interaction liquid chromatography (HILIC) coupled with electrospray ionization (ESI) and Fourier-transform mass spectrometry (FTMS; HILIC-ESI-FTMS) was employed to discriminate the phospholipidome profiles of fillets extracts of wild-caught from farmed gilthead sea breams.</p>
</div>
<div>
<h3>Results:</h3>
<p>The untargeted approach led to the annotation of a total of 216 phospholipids (PLs), namely 65 phosphatidylethanolamines (PEs), 27 lyso-PEs (LPEs), 61 phosphatidylcholines (PCs), 34 lyso-PCs (LPCs), and 29 sphingomyelins (SMs). Untargeted lipidomics data were investigated by principal component analysis (PCA) and <em>K</em>-means clustering. Lyso-PLs (LPLs) of PEs and PCs including ether-linked side chains were found as discriminating markers between the two types of fish samples. The PLs that were most responsible for distinguishing between the lipid extracts of farmed and wild <em>S. aurata</em> fillets were successfully characterized by tandem mass spectrometry (MS/MS). The analysis revealed that wild fillet lipid extracts contained some PE exhibiting ether bonds (PE P-), <em>viz</em>. 16:0, 18:0, 18:1, and 18:2 and polyunsaturated fatty acyl chains (i.e., 22:6 and 22:5). In farmed species, the estimated abundance ratios of fatty acyl chains 20:4/18:2 and 22:6/20:5 were 0.9 and 0.05, respectively. However, in wild-caught fish, these ratios were found to be two-fold higher and four-fold higher, respectively.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>This work demonstrates that the combination of HILIC-ESI-FTMS and chemometrics can serve as a valuable tool for evaluating fish authenticity and assessing quality concerns by monitoring specific lipid ratios.</p>
</div>

            [Names] => Sara Granafei ... Tommaso R.I. Cataldi
            [Doi] => 10.37349/eff.2023.00008
            [Published] => June 30, 2023
            [Viewed] => 388
            [Downloaded] => 37
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00008
            [Inline] => 1
            [Type] => 1
            [Issue] => 2
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:83–100
            [Recommend] => 0
            [Keywords] =>  Hydrophilic interaction liquid chromatography, tandem mass spectrometry, food, phospholipids, fish, 
<em>Sparus aurata</em>

            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10108
            [ris] => https://www.explorationpub.com/uploads/Article/A10108/a7a2f8d40e19e961864bfd4adc56c76e.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10108/5c700ec509404e2d58f3e305d8fa7be0.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Granafei S, Calvano CD, Ventura G, Castellaneta A, Losito I, Cataldi TRI. Untargeted lipidomics for evaluating fish authenticity: the case of wild-caught and farmed species of <i>Sparus aurata</i>. Explor Foods Foodomics. 2023;1:83–100. <a href="https://doi.org/10.37349/eff.2023.00008">https://doi.org/10.37349/eff.2023.00008</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-06-30 17:18:22
            [Bib_Time] => 2023-06-30 17:18:22
            [KeysWordContens] => Untargeted lipidomics for evaluating fish authenticity: the case of wild-caught and farmed species of Sparus aurata, Hydrophilic interaction liquid chromatography, tandem mass spectrometry, food, phospholipids, fish, 
Sparus aurata
,

Aim:
This study aims to develop sensitive and reliable analytical technologies to enable the distinction between wild-caught and farmed fish through appropriate molecular markers to protect consumers from fraudulent fish labelling. Gilthead sea bream, Sparus aurata L. (S. aurata L.), is a very common fish used as foodstuff worldwide and globally produced in aquaculture in the Mediterranean basin. Wild-caught and farmed species are very different in feed and lifestyle and the quality and safety of these products strongly depend on fish growth, processing history, and storage conditions.


Methods:
Hydrophilic interaction liquid chromatography (HILIC) coupled with electrospray ionization (ESI) and Fourier-transform mass spectrometry (FTMS; HILIC-ESI-FTMS) was employed to discriminate the phospholipidome profiles of fillets extracts of wild-caught from farmed gilthead sea breams.


Results:
The untargeted approach led to the annotation of a total of 216 phospholipids (PLs), namely 65 phosphatidylethanolamines (PEs), 27 lyso-PEs (LPEs), 61 phosphatidylcholines (PCs), 34 lyso-PCs (LPCs), and 29 sphingomyelins (SMs). Untargeted lipidomics data were investigated by principal component analysis (PCA) and K-means clustering. Lyso-PLs (LPLs) of PEs and PCs including ether-linked side chains were found as discriminating markers between the two types of fish samples. The PLs that were most responsible for distinguishing between the lipid extracts of farmed and wild S. aurata fillets were successfully characterized by tandem mass spectrometry (MS/MS). The analysis revealed that wild fillet lipid extracts contained some PE exhibiting ether bonds (PE P-), viz. 16:0, 18:0, 18:1, and 18:2 and polyunsaturated fatty acyl chains (i.e., 22:6 and 22:5). In farmed species, the estimated abundance ratios of fatty acyl chains 20:4/18:2 and 22:6/20:5 were 0.9 and 0.05, respectively. However, in wild-caught fish, these ratios were found to be two-fold higher and four-fold higher, respectively.


Conclusions:
This work demonstrates that the combination of HILIC-ESI-FTMS and chemometrics can serve as a valuable tool for evaluating fish authenticity and assessing quality concerns by monitoring specific lipid ratios.

,Sara Granafei ... Tommaso R.I. Cataldi
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 21
        )

    [8] => Array
        (
            [ArticleId] => 699
            [Create_Time] => 2023-08-23
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202308/20230823090457.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A10109/10109.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A10109/10109.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A10109/10109_cover.png
            [JournalsId] => 12
            [Title] => 
<sup>1</sup>H NMR-based metabolomics of cacao pod husk: profile comparison of three drying treatments
            [Abstract] => Aim:
The aim of this study is to apply untargeted proton nuclear magnetic resonance (<sup>1</sup>H NMR) and chemometric analysis to obtain the cacao pod husk (CPH) fingerprint and evaluate the effect of deh
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>The aim of this study is to apply untargeted proton nuclear magnetic resonance (<sup>1</sup>H NMR) and chemometric analysis to obtain the cacao pod husk (CPH) fingerprint and evaluate the effect of dehydration in the CPH metabolome.</p>
</div>
<div>
<h3>Methods:</h3>
<p>Phosphate buffer extracts (pH 6.5) were obtained and measured using a one-dimension (1D) <sup>1</sup>H NMR spectrometry. The 1D <sup>1</sup>H NMR spectra were recorded without spinning and using the presaturation (PRESAT) pulse sequence to suppress the residual H<sub>2</sub>O signal. The 3-(trimethylsilyl) propionic-2,2,3,3-d<sub>4 </sub>acid sodium salt (TSP) was used as an internal reference. Analysis of processed data, applying an orthogonal projection on latent structure-discriminant analysis (OPLS-DA) model was used to highlight significant differences between the three dehydration treatments. Signal assignment of CPH metabolites was carried out based on the coupling constant, software simulation prediction, published data comparison, and metabolomics databases.</p>
</div>
<div>
<h3>Results:</h3>
<p>A total of 25 compounds were detected by <sup>1</sup>H NMR, methylxanthines, sugars, some amino acids, fatty acids, and organic acids were found among the identified compounds. The fingerprint spectra of the three dehydration methods were clustered separately discriminating the metabolome profile of each of the dehydration treatments, finding that metabolome remarkably differed in theanine, myristic acid, fumaric acid, and aspartic acid composition.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>An untargeted metabolomics to obtain the fingerprint of CPH was successfully established. A <sup>1</sup>H NMR spectra with a detailed signal assignment aided to identify 25 metabolites present in CPH fresh and dried by different methods. The results complement the information about CPH composition and how it is affected by the temperature used during the dehydration process. The multivariate analysis points out that freeze drying (FD) preserves the metabolites better than microwave drying (MWD) or hot air drying (HAD). FD and MWD are similar in composition maintaining most of the compounds after drying.</p>
</div>

            [Names] => Demelza Nayelli Villalón-López ... Lourdes Valadez-Carmona
            [Doi] => 10.37349/eff.2023.00009
            [Published] => August 23, 2023
            [Viewed] => 150
            [Downloaded] => 8
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00009
            [Inline] => 1
            [Type] => 1
            [Issue] => 3
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:101–114
            [Recommend] => 0
            [Keywords] =>  Cacao pod husk fingerprint, proton nuclear magnetic resonance metabolomics, myristic acid, fumaric acid, theanine
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 10109
            [ris] => https://www.explorationpub.com/uploads/Article/A10109/91fe3ce15fe27983c04ef7a6c9f0e268.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A10109/d50536df99ea1a59cbba74fb915a7362.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Villalón-López DN, Hernández-Ortega M, Ortiz-Moreno A, Ceballos G, Zepeda-Vallejo G, Valadez-Carmona L. <sup>1</sup>H NMR-based metabolomics of cacao pod husk: profile comparison of three drying treatments. Explor Foods Foodomics. 2023;1:101–14. <a href="https://doi.org/10.37349/eff.2023.00009">https://doi.org/10.37349/eff.2023.00009</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-08-23 10:03:49
            [Bib_Time] => 2023-08-23 10:03:49
            [KeysWordContens] => 
1H NMR-based metabolomics of cacao pod husk: profile comparison of three drying treatments, Cacao pod husk fingerprint, proton nuclear magnetic resonance metabolomics, myristic acid, fumaric acid, theanine,

Aim:
The aim of this study is to apply untargeted proton nuclear magnetic resonance (1H NMR) and chemometric analysis to obtain the cacao pod husk (CPH) fingerprint and evaluate the effect of dehydration in the CPH metabolome.


Methods:
Phosphate buffer extracts (pH 6.5) were obtained and measured using a one-dimension (1D) 1H NMR spectrometry. The 1D 1H NMR spectra were recorded without spinning and using the presaturation (PRESAT) pulse sequence to suppress the residual H2O signal. The 3-(trimethylsilyl) propionic-2,2,3,3-d4 acid sodium salt (TSP) was used as an internal reference. Analysis of processed data, applying an orthogonal projection on latent structure-discriminant analysis (OPLS-DA) model was used to highlight significant differences between the three dehydration treatments. Signal assignment of CPH metabolites was carried out based on the coupling constant, software simulation prediction, published data comparison, and metabolomics databases.


Results:
A total of 25 compounds were detected by 1H NMR, methylxanthines, sugars, some amino acids, fatty acids, and organic acids were found among the identified compounds. The fingerprint spectra of the three dehydration methods were clustered separately discriminating the metabolome profile of each of the dehydration treatments, finding that metabolome remarkably differed in theanine, myristic acid, fumaric acid, and aspartic acid composition.


Conclusions:
An untargeted metabolomics to obtain the fingerprint of CPH was successfully established. A 1H NMR spectra with a detailed signal assignment aided to identify 25 metabolites present in CPH fresh and dried by different methods. The results complement the information about CPH composition and how it is affected by the temperature used during the dehydration process. The multivariate analysis points out that freeze drying (FD) preserves the metabolites better than microwave drying (MWD) or hot air drying (HAD). FD and MWD are similar in composition maintaining most of the compounds after drying.

,Demelza Nayelli Villalón-López ... Lourdes Valadez-Carmona
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 45
        )

    [9] => Array
        (
            [ArticleId] => 719
            [Create_Time] => 2023-08-28
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202309/20230901035108.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A101010/101010.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A101010/101010.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A101010/101010_cover.png
            [JournalsId] => 12
            [Title] => Isolation, characterization, and encapsulation of a lupeol-rich fraction obtained from the hexanic extract of <em>Coccoloba uvifera</em> L. leaves
            [Abstract] => Aim:
This study aimed to isolate, characterize, and encapsulate a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves to evaluate its potential use in nutraceuti
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>This study aimed to isolate, characterize, and encapsulate a lupeol-rich fraction obtained from the hexanic extract of <em>Coccoloba uvifera</em> L. leaves to evaluate its potential use in nutraceutical or pharmaceutical applications.</p>
</div>
<div>
<h3>Methods:</h3>
<p>The <em>C. uvifera</em> leaf extract was fractionated by column chromatography and the presence of lupeol was assessed by thin layer chromatography, attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy, nuclear magnetic resonance (NMR), and liquid chromatography-mass spectrometry (LC-MS). Additionally, the lupeol-rich fraction was characterized according to its antioxidant capacity and cytotoxicity. Finally, this fraction was encapsulated into electrospun nanofibers made of high degree of polymerization agave fructans (HDPAF) combined with polyethylene oxide (PEO). The obtained nanofibers were characterized in terms of morphology, chemical composition, and <em>in vitro</em> permeability using the Caco-2 cell line.</p>
</div>
<div>
<h3>Results:</h3>
<p>Fraction 6 showed a 77% of lupeol, quantified by chromatography, and presented a 7.3% inhibition of 2,2-diphenyl-1-picrylhydrazyl (DPPH). 100 µg/mL of fraction 6 showed a decrease in Caco-2 cell viability. Finally, fraction 6 was encapsulated into electrospun nanofibers, which showed an increase in the apparent permeability of the lupeol present in fraction 6 in Caco-2 cells in comparison to neat fraction 6.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>It was possible to isolate and encapsulate a lupeol-rich fraction from <em>C. uvifera</em> into electrospun nanofibers, which allows the increasing the apparent permeability of lupeol, and consequently, they could be used for nutraceutical or pharmaceutical applications.</p>
</div>

            [Names] => Carla N. Cruz-Salas ... Juan A. Ragazzo-Sánchez
            [Doi] => 10.37349/eff.2023.00010
            [Published] => August 28, 2023
            [Viewed] => 148
            [Downloaded] => 11
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00010
            [Inline] => 1
            [Type] => 1
            [Issue] => 3
            [Topic] => 108
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:115–129
            [Recommend] => 0
            [Keywords] =>  
<em>Coccoloba uvifera</em> leaves, lupeol-rich fraction, cytotoxicity, electrospinning, 
<em>in vitro </em>Caco-2 permeability
            [DetailTitle] => Natural Products in Health and Disease
            [DetailUrl] => https://www.explorationpub.com/Journals/eff/Special_Issues/108
            [Id] => 101010
            [ris] => https://www.explorationpub.com/uploads/Article/A101010/bc131a820b3bdea7904c9119a438b3ab.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A101010/c5b0958e75d0971b0a33fc75c76b2a89.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Cruz-Salas CN, Evtoski Z, Calderón-Santoyo M, Lagarón JM, Prieto C, Ragazzo-Sánchez JA. Isolation, characterization, and encapsulation of a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves. Explor Foods Foodomics. 2023;1:115–29. <a href="https://doi.org/10.37349/eff.2023.00010">https://doi.org/10.37349/eff.2023.00010</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-08-28 05:30:06
            [Bib_Time] => 2023-08-28 05:30:06
            [KeysWordContens] => Isolation, characterization, and encapsulation of a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves, 
Coccoloba uvifera leaves, lupeol-rich fraction, cytotoxicity, electrospinning, 
in vitro Caco-2 permeability,

Aim:
This study aimed to isolate, characterize, and encapsulate a lupeol-rich fraction obtained from the hexanic extract of Coccoloba uvifera L. leaves to evaluate its potential use in nutraceutical or pharmaceutical applications.


Methods:
The C. uvifera leaf extract was fractionated by column chromatography and the presence of lupeol was assessed by thin layer chromatography, attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy, nuclear magnetic resonance (NMR), and liquid chromatography-mass spectrometry (LC-MS). Additionally, the lupeol-rich fraction was characterized according to its antioxidant capacity and cytotoxicity. Finally, this fraction was encapsulated into electrospun nanofibers made of high degree of polymerization agave fructans (HDPAF) combined with polyethylene oxide (PEO). The obtained nanofibers were characterized in terms of morphology, chemical composition, and in vitro permeability using the Caco-2 cell line.


Results:
Fraction 6 showed a 77% of lupeol, quantified by chromatography, and presented a 7.3% inhibition of 2,2-diphenyl-1-picrylhydrazyl (DPPH). 100 µg/mL of fraction 6 showed a decrease in Caco-2 cell viability. Finally, fraction 6 was encapsulated into electrospun nanofibers, which showed an increase in the apparent permeability of the lupeol present in fraction 6 in Caco-2 cells in comparison to neat fraction 6.


Conclusions:
It was possible to isolate and encapsulate a lupeol-rich fraction from C. uvifera into electrospun nanofibers, which allows the increasing the apparent permeability of lupeol, and consequently, they could be used for nutraceutical or pharmaceutical applications.

,Carla N. Cruz-Salas ... Juan A. Ragazzo-Sánchez
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 46
        )

    [10] => Array
        (
            [ArticleId] => 725
            [Create_Time] => 2023-08-29
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            [Title] => 
<em>Azadirachta indica</em> A. Juss (neem) phenolic extract inhibits human B-lymphoblastoid cells growth via cell cycle arrest, apoptosis induction, and DNA damage
            [Abstract] => Aim:
As far as is known, the pharmaceutical effects of neem on human B-lymphoblastoid (TK6) cells have not been studied until now. Hence, the present study aimed to obtain neem phenolic extracts 
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>As far as is known, the pharmaceutical effects of neem on human B-lymphoblastoid (TK6) cells have not been studied until now. Hence, the present study aimed to obtain neem phenolic extracts for inhibits the proliferation of TK6 cells and explore some possible underlying mechanisms involved in these effects.</p>
</div>
<div>
<h3>Methods:</h3>
<p>Hexane extract (HE) was obtained in the first step. After that, the residual hexane was removed from the neem. The dried neem sample was used in a new extraction for obtaining the ethyl acetate extract (EAE). Total phenolic compounds (TPC) and total flavonoid contents (TFC) were determined by spectrophotometric methods. Lactate dehydrogenase (LDH) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) tests were used to evaluate the cytotoxicity in TK6 cells. The stop at G0/G1 cell cycle and inducing apoptosis in the TK6 cells were analyzed by flow cytometry. For deoxyribonucleic acid (DNA) damage evaluation, the alkaline comet test was used.</p>
</div>
<div>
<h3>Results:</h3>
<p>The higher TFC (65.50 mg/g of extract ± 1.17 mg/g of extract) and TPC (52.08 mg of extract ± 0.88 mg of extract) were obtained in EAE compared to HE that was obtained TFC of 14.61 mg/g of extract ± 0.60 mg/g of extract and TPC of 3.20 mg/g of extract ± 1.20 mg/g of extract. EAE was more significantly cytotoxic to TK6 cells than HE. The apoptosis induction was higher after exposure to 15.0 µg/mL of EAE (11.29%) in comparison to 15.0 µg/mL of HE (2.52%). The G0/G1 phase increased from 72% negative control (NC) to 83% after treatment with neem extracts (15 µg/mL). Neem extracts were also able to cause DNA strand breaks in TK6 cells.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>The extraction residue from neem leaf after hexane extraction is a source important of cytotoxic and genotoxic molecules against TK6 cells, the results also can suggest that the toxic effects in TK6 cells can be provided most likely due to the presence of high content of TPC from neem extracts.</p>
</div>

            [Names] => Klebson Silva Santos ... Maria Beatriz Pinto Prior Oliveira
            [Doi] => 10.37349/eff.2023.00011
            [Published] => August 29, 2023
            [Viewed] => 136
            [Downloaded] => 17
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00011
            [Inline] => 1
            [Type] => 1
            [Issue] => 3
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:130–142
            [Recommend] => 0
            [Keywords] =>  Medicinal plant, bioactive extracts, sequential pressurized fluids, antiproliferative effect, human B-lymphoblastoid cells
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 101011
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            [bib] => https://www.explorationpub.com/uploads/Article/A101011/601779b1f74eda547be530b8fdc521b7.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Santos KS, Costa C, Bessa MJ, Teixeira JP, Muniz AVCdS, Padilha FF, Dariva C, Oliveira MBPP. <i>Azadirachta indica</i> A. Juss (neem) phenolic extract inhibits human B-lymphoblastoid cells growth via cell cycle arrest, apoptosis induction, and DNA damage. Explor Foods Foodomics. 2023;1:130–42.  <a href="https://doi.org/10.37349/eff.2023.00011">https://doi.org/10.37349/eff.2023.00011</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-08-29 07:31:49
            [Bib_Time] => 2023-08-29 07:31:49
            [KeysWordContens] => 
Azadirachta indica A. Juss (neem) phenolic extract inhibits human B-lymphoblastoid cells growth via cell cycle arrest, apoptosis induction, and DNA damage, Medicinal plant, bioactive extracts, sequential pressurized fluids, antiproliferative effect, human B-lymphoblastoid cells,

Aim:
As far as is known, the pharmaceutical effects of neem on human B-lymphoblastoid (TK6) cells have not been studied until now. Hence, the present study aimed to obtain neem phenolic extracts for inhibits the proliferation of TK6 cells and explore some possible underlying mechanisms involved in these effects.


Methods:
Hexane extract (HE) was obtained in the first step. After that, the residual hexane was removed from the neem. The dried neem sample was used in a new extraction for obtaining the ethyl acetate extract (EAE). Total phenolic compounds (TPC) and total flavonoid contents (TFC) were determined by spectrophotometric methods. Lactate dehydrogenase (LDH) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) tests were used to evaluate the cytotoxicity in TK6 cells. The stop at G0/G1 cell cycle and inducing apoptosis in the TK6 cells were analyzed by flow cytometry. For deoxyribonucleic acid (DNA) damage evaluation, the alkaline comet test was used.


Results:
The higher TFC (65.50 mg/g of extract ± 1.17 mg/g of extract) and TPC (52.08 mg of extract ± 0.88 mg of extract) were obtained in EAE compared to HE that was obtained TFC of 14.61 mg/g of extract ± 0.60 mg/g of extract and TPC of 3.20 mg/g of extract ± 1.20 mg/g of extract. EAE was more significantly cytotoxic to TK6 cells than HE. The apoptosis induction was higher after exposure to 15.0 µg/mL of EAE (11.29%) in comparison to 15.0 µg/mL of HE (2.52%). The G0/G1 phase increased from 72% negative control (NC) to 83% after treatment with neem extracts (15 µg/mL). Neem extracts were also able to cause DNA strand breaks in TK6 cells.


Conclusions:
The extraction residue from neem leaf after hexane extraction is a source important of cytotoxic and genotoxic molecules against TK6 cells, the results also can suggest that the toxic effects in TK6 cells can be provided most likely due to the presence of high content of TPC from neem extracts.

,Klebson Silva Santos ... Maria Beatriz Pinto Prior Oliveira
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 80
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    [11] => Array
        (
            [ArticleId] => 761
            [Create_Time] => 2023-08-31
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202309/20230906051941.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A101013/101013.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A101013/101013.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A101013/101013_cover.png
            [JournalsId] => 12
            [Title] => Investigation the spatial distribution of polyphenols and metabolomic profiling of apple
            [Abstract] => Aim:
In this study, Polyphenol and chemical profiles in core, pulp, and peel of 7 apple varieties [Fuji (FS), Qinguan (QG), Qingping (QP), Jinshuai (JS), Gala (GL), Changmiou (CMO), and Huahong (
            [AbstractComplete] => 
<div>
<h3>Aim:</h3>
<p>In this study, Polyphenol and chemical profiles in core, pulp, and peel of 7 apple varieties [Fuji (FS), Qinguan (QG), Qingping (QP), Jinshuai (JS), Gala (GL), Changmiou (CMO), and Huahong (HH)] were comparatively studied to distinguish the different metabolism biomarkers in the three parts of apple fruit.</p>
</div>
<div>
<h3>Methods:</h3>
<p>This study investigated the distribution of 15 polyphenolic compounds using a combination of multivariate analysis and ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS).</p>
</div>
<div>
<h3>Results:</h3>
<p>chlorogenic acid, catechin, epicatechin, phloretin were the most abundant components. While phloretin was the dominant component in core, chlorogenic acid was the main phenolic compound in pulp, and quercetin was mainly found in apple peel. The multivariate analysis showed that the chemical profile of peel was significantly distinct from that of apple pulp and core, whereas apple pulp and core overlapped with each other. The difference attributed to the compounds that were predicted from ultra-high performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS), which were remarkably different (<em>P </em>&lt; 0.05) and belong to polyphenol.</p>
</div>
<div>
<h3>Conclusions:</h3>
<p>It indicates that the potential superior biomarker of polyphenols is to differentiate the products from apple core, pulp, and peel respectively. This research provided an insight on the polyphenolic profile of core, pulp, and peel of apple fruits.</p>
</div>

            [Names] => Xuan Li ... Jinfeng Bi
            [Doi] => 10.37349/eff.2023.00013
            [Published] => August 31, 2023
            [Viewed] => 144
            [Downloaded] => 10
            [Subject] => Original Article
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00013
            [Inline] => 1
            [Type] => 1
            [Issue] => 3
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:162–177
            [Recommend] => 0
            [Keywords] =>  Apple peel, core, pulp polyphenols, chemical profile, metabolomics
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 101013
            [ris] => https://www.explorationpub.com/uploads/Article/A101013/c493a46d740c57d518a1bd52e3bf1896.ris
            [bib] => https://www.explorationpub.com/uploads/Article/A101013/611df5dbbf4d99e838a5843e7ae93b0a.bib
            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Li X, Wang WY, Hu JX, Bi J. Investigation the spatial distribution of polyphenols and metabolomic profiling of apple. Explor Foods Foodomics. 2023;1:162–77. <a href="https://doi.org/10.37349/eff.2023.00013">https://doi.org/10.37349/eff.2023.00013</a>
            [Jindex] => 0
            [CName] => JinfengBi,
            [CEmail] => bjfcaas@126.com,
            [Ris_Time] => 2023-09-01 02:30:53
            [Bib_Time] => 2023-09-01 02:30:53
            [KeysWordContens] => Investigation the spatial distribution of polyphenols and metabolomic profiling of apple, Apple peel, core, pulp polyphenols, chemical profile, metabolomics,

Aim:
In this study, Polyphenol and chemical profiles in core, pulp, and peel of 7 apple varieties [Fuji (FS), Qinguan (QG), Qingping (QP), Jinshuai (JS), Gala (GL), Changmiou (CMO), and Huahong (HH)] were comparatively studied to distinguish the different metabolism biomarkers in the three parts of apple fruit.


Methods:
This study investigated the distribution of 15 polyphenolic compounds using a combination of multivariate analysis and ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS).


Results:
chlorogenic acid, catechin, epicatechin, phloretin were the most abundant components. While phloretin was the dominant component in core, chlorogenic acid was the main phenolic compound in pulp, and quercetin was mainly found in apple peel. The multivariate analysis showed that the chemical profile of peel was significantly distinct from that of apple pulp and core, whereas apple pulp and core overlapped with each other. The difference attributed to the compounds that were predicted from ultra-high performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS), which were remarkably different (P < 0.05) and belong to polyphenol.


Conclusions:
It indicates that the potential superior biomarker of polyphenols is to differentiate the products from apple core, pulp, and peel respectively. This research provided an insight on the polyphenolic profile of core, pulp, and peel of apple fruits.

,Xuan Li ... Jinfeng Bi
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 46
        )

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            [ArticleId] => 760
            [Create_Time] => 2023-08-30
            [zipUrl] => https://www.explorationpub.com/uploads/zip/202308/20230830023107.zip
            [xmlUrl] => https://www.explorationpub.com/uploads/Article/A101012/101012.xml
            [pdfUrl] => https://www.explorationpub.com/uploads/Article/A101012/101012.pdf
            [coverUrl] => https://www.explorationpub.com/uploads/Article/A101012/101012_cover.png
            [JournalsId] => 12
            [Title] => Intelligent point of care test for food safety via a smartphone
            [Abstract] => The on-site, rapid, and intelligence detection methods are the wave in food safety. Recently, intelligent point-of-care test (iPOCT) methods serve as a promising alternative for advanced monitoring 
            [AbstractComplete] => 
<p>The on-site, rapid, and intelligence detection methods are the wave in food safety. Recently, intelligent point-of-care test (iPOCT) methods serve as a promising alternative for advanced monitoring in food safety. By integrating smartphones with various detection methods, iPOCT methods demonstrate unique merits. Compared with lab-dependent instruments, iPOCT strategies have a short turnaround time (several minutes), high accuracy (μm level or less), and portability (smartphones). This work discussed principles of optical and electrical iPOCT methods, including absorbing light, fluorescence, chemiluminescence, potentiometry, voltammetry, impedance spectroscopy, and amperometry. The review emphasizes the practical applications for testing chemical and biological hazards in complex food matrices. The commercialization, challenges, and future trends of iPOCT are discussed as well.</p>

            [Names] => Le Zhang ... Zhaowei Zhang
            [Doi] => 10.37349/eff.2023.00012
            [Published] => August 30, 2023
            [Viewed] => 149
            [Downloaded] => 10
            [Subject] => Review
            [Year] => 2023
            [CiteUrl] => https://api.crossref.org/works/10.37349/eff.2023.00012
            [Inline] => 1
            [Type] => 1
            [Issue] => 3
            [Topic] => 0
            [TitleAbbr] => Explor Foods Foodomics.
            [Pages] => 2023;1:143–161
            [Recommend] => 0
            [Keywords] =>  Food safety, hazardous factors, intelligent point-of-care test, commercialization, opportunities
            [DetailTitle] => 
            [DetailUrl] => 
            [Id] => 101012
            [ris] => https://www.explorationpub.com/uploads/Article/A101012/ce5594723ec66de46ff4b0301f26100b.ris
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            [ens] => 
            [Cited] => 0
            [Cited_Time] => 
            [CitethisArticle] => Zhang L, Yang X, Liang M, Tian Z, Zhang Z. Intelligent point of care test for food safety via a smartphone. Explor Foods Foodomics. 2023;1:143–61. <a href="https://doi.org/10.37349/eff.2023.00012">https://doi.org/10.37349/eff.2023.00012</a>
            [Jindex] => 0
            [CName] => 
            [CEmail] => 
            [Ris_Time] => 2023-08-29 07:41:28
            [Bib_Time] => 2023-08-29 07:41:28
            [KeysWordContens] => Intelligent point of care test for food safety via a smartphone, Food safety, hazardous factors, intelligent point-of-care test, commercialization, opportunities,
The on-site, rapid, and intelligence detection methods are the wave in food safety. Recently, intelligent point-of-care test (iPOCT) methods serve as a promising alternative for advanced monitoring in food safety. By integrating smartphones with various detection methods, iPOCT methods demonstrate unique merits. Compared with lab-dependent instruments, iPOCT strategies have a short turnaround time (several minutes), high accuracy (μm level or less), and portability (smartphones). This work discussed principles of optical and electrical iPOCT methods, including absorbing light, fluorescence, chemiluminescence, potentiometry, voltammetry, impedance spectroscopy, and amperometry. The review emphasizes the practical applications for testing chemical and biological hazards in complex food matrices. The commercialization, challenges, and future trends of iPOCT are discussed as well.
,Le Zhang ... Zhaowei Zhang
            [PublishedText] => Published
            [IsEdit] => 0
            [AccountId] => 45
        )

)