• Special Issue Topic

    Perspectives on Causal Mechanisms, Prevention and Management of Pediatric Obesity and Related Comorbidities

    Submission Deadline: October 15, 2022

    Guest Editors

    Prof. Pietro Vajro E-Mail

    Full Professor, Pediatrics, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Italy

    Dr. Claudia Mandato E-Mail

    Associate Professor, Pediatrics, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Italy

    About the Special Issue

    Pediatric obesity is the most prevalent nutritional disorder in children and adolescents worldwide, with a relentless diffusion among all social categories, which reflects our still imperfect understanding of the disease. Due to a) the participation of several systemic and psychosocial comorbidities, and b) its tracking into adulthood, this condition represents a relevant and still unresolved public health challenge requiring more and more extraordinary multidisciplinary efforts.

    Recent progress in obesity genetics, epigenetics, novel signaling pathways, and neurohormonal gut-liver-systemic circulation-brain axis appear mounting. The intent of this special issue is therefore to gather novel data and insights from basic and clinical science researchers in multiple areas to advance our knowledge on the causal mechanisms beyond the obvious unbalance between energy intake/expenditure, possibly capable of fostering novel/improved approaches for disease prevention and management. We expect contributions on the whole spectrum of pediatric obesity related conditions such as metabolic syndrome, sleep-disordered breathing, exercise intolerance, orthopedic diseases, liver and gastroesophageal disease, polycystic ovaries, idiopathic intracranial hypertension, psychopathologies, and other common and less common comorbidities.  

    We encourage all investigators who operate in the pediatric obesity field to submit original research articles, reviews, systematic reviews, and meta-analyses to this Special Issue with the goal of expanding our state of the art knowledge and opening new research avenues.

    Keywords: pediatric obesity, obesity comorbidities, pathomechanisms, prevention, management, nutrition, lifestyle

    Call for Papers

    Published Articles

    Open Access
    Original Article
    Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma
    Aim: Being overweight and obesity are factors in the negative modification of bronchial asthma (BA). The mechanisms of the aggravating effect of obesity on the course of BA have not yet been fully determined, but include changes i [...] Read more.
    Regina N. Khramova ... Olga V. Khaletskaya
    Published: May 30, 2023 Explor Med. 2023;4:323–332
    DOI: https://doi.org/10.37349/emed.2023.00143
    Times Cited: 0
    Open Access
    Original Article
    Can we estimate the causal effects of diet and sedentary behavior on schoolchildren’s overweight/obesity from observational studies?
    Aim: To investigate the causal impact of diet and sedentary behavior on Brazilian schoolchildren’s overweight/obesity using the data from observational studies. Methods: Annual cros [...] Read more.
    Emil Kupek
    Published: April 27, 2023 Explor Med. 2023;4:272–285
    DOI: https://doi.org/10.37349/emed.2023.00139
    Times Cited: 0
    Open Access
    Original Article
    Abnormal glucose tolerance in children: oral glucose tolerance test is fit-for-purpose
    Aim: Childhood obesity is accompanied by an increased prevalence of abnormal glucose tolerance (AGT) including the prediabetes states. This study aims to investigate and evaluate the use of oral gl [...] Read more.
    Vivian Yuet Ho Law ... Louis Tsz Wang Chan
    Published: April 26, 2023 Explor Med. 2023;4:235–245
    DOI: https://doi.org/10.37349/emed.2023.00136
    Times Cited: 0