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Exploration of Medicine
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    Special Issue Topic

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    Submission Deadline:

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    January 01, 1970

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    Guest Editor

    About the Special Issue

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    Published Articles

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    Perspective
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    Alessandro Poggi, Maria Raffaella Zocchi
    Published: April 28, 2022 Explor Immunol. 2022;2:220–228
    DOI: https://doi.org/10.37349/ei.2022.00047
    View:221
    Download:18
    Times Cited: 0
    Open Access
    Original Article
    Single-cell differentiation trajectories define early stages of a human cutaneous T-cell lymphoma
    Aim: The aim of this article is to characterize in detail the γδ T lymphocytes from an adult patient with primary cutaneous T-cell lymphoma of γδ s [...] Read more.
    Juan-Pablo Cerapio ... Jean-Jacques Fournie
    Published: April 15, 2022 Explor Immunol. 2022;2:185–199
    DOI: https://doi.org/10.37349/ei.2022.00044
    View:241
    Download:16
    Times Cited: 0
    Open Access
    Review
    Augmenting human gamma delta lymphocytes for cancer therapy with chimeric antigen receptors
    Gamma delta lymphocytes (γδ T) sit at the interface between innate and adaptive immunity. They have the capacity to recognize cancer cells by interaction of their surface receptors with an array of cancer cell surface target ant [...] Read more.
    Gabrielle M. Ferry, John Anderson
    Published: March 17, 2022 Explor Immunol. 2022;2:168–179
    DOI: https://doi.org/10.37349/ei.2022.00042
    View:333
    Download:30
    Times Cited: 0
    Open Access
    Review
    The role of γδ T cells in the context of allogeneic stem cell transplantation
    Allogeneic stem cell transplantation is currently the only curative approach for a variety of malignant and non-malignant diseases. In the early transplant era, the intent of this treatment was to a [...] Read more.
    Rupert Handgretinger ... Manon Queudeville
    Published: March 16, 2022 Explor Immunol. 2022;2:157–167
    DOI: https://doi.org/10.37349/ei.2022.00041
    View:309
    Download:28
    Times Cited: 0
    Open Access
    Review
    Novel insights based on the plasticity of γδ T cells in the tumor microenvironment
    γδ T cells express unique T cell receptor (TCR) γ and TCR δ chains, with structural and functional heterogeneity. Taking advantage of the diverse γδ TCR repertoire or other ligand-receptor interactions, γδ T cells can reco [...] Read more.
    Yue Wang ... Wei He
    Published: February 24, 2022 Explor Immunol. 2022;2:98–132
    DOI: https://doi.org/10.37349/ei.2022.00039
    View:444
    Download:48
    Times Cited: 0
    Open Access
    Review
    γδ T cell costimulatory ligands in antitumor immunity
    Antitumor immunity relies on the ability of T cells to recognize and kill tumor targets. γδ T cells are a specialized subset of T cells that predominantly localizes to non-ly [...] Read more.
    Joseph M. McGraw, Deborah A. Witherden
    Published: February 24, 2022 Explor Immunol. 2022;2:79–97
    DOI: https://doi.org/10.37349/ei.2022.00038
    View:340
    Download:43
    Times Cited: 0
    Open Access
    Review
    Tumor-associated protein ligands recognized by human γδ T cell receptor and their implications in cancer therapy
    In recent years, immunologists have been working to utilize the functional mechanism of the immune system to research new tumor treatment methods and achieved a major breakthrough in 2013, which was [...] Read more.
    Chang Liu ... Wei He
    Published: February 22, 2022 Explor Immunol. 2022;2:64–78
    DOI: https://doi.org/10.37349/ei.2022.00037
    View:432
    Download:27
    Times Cited: 0
    Open Access
    Review
    The microbiota is a potential mediator of the crosstalk between γδ T cells and tumors
    γδ T cells are one of the immune cell types that express antigen receptors. γδ T cells are able to recognize pathogens or cancer cells independently o [...] Read more.
    Huidi Wang ... Jia Yin
    Published: February 18, 2022 Explor Immunol. 2022;2:48–63
    DOI: https://doi.org/10.37349/ei.2022.00036
    View:320
    Download:17
    Times Cited: 0
    Open Access
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    γδT cells: alternative treasure in antitumor immunity
    In recent decades, abundant methods for targeted tumor cell immunotherapy have been developed. It was recently discovered that excellent curative effects observed in hematological tumors cannot be achieved in solid tumors, as seri [...] Read more.
    Xiangjin Zhang ... Wei He
    Published: February 17, 2022 Explor Immunol. 2022;2:32–47
    DOI: https://doi.org/10.37349/ei.2022.00035
    View:364
    Download:23
    Times Cited: 0