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Exploration of Medicine
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    Special Issue Topic

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    Submission Deadline:

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    January 01, 1970

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    Guest Editor

    About the Special Issue

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    Published Articles

    Open Access
    Review
    Antibody-drug conjugates: beyond current approvals and potential future strategies
    The recent approvals for antibody-drug conjugates (ADCs) in multiple malignancies in recent years have fuelled the ongoing development of this class of drugs. These novel agents combine the benefits [...] Read more.
    Siddharth Menon ... Hui K. Gan
    Published: April 28, 2022 Explor Target Antitumor Ther. 2022;3:252–277
    DOI: https://doi.org/10.37349/etat.2022.00082
    View:359
    Download:31
    Times Cited: 0
    Open Access
    Review
    Advancing antibody-drug conjugates in gynecological malignancies: myth or reality?
    Antibody-drug conjugates (ADCs) represent a new class of therapeutic agents designed to target specific antigens on tumor cells, combining the specificity of monoclonal antibodies to the cytotoxicit [...] Read more.
    Marta Nerone ... Ilaria Colombo
    Published: April 19, 2022 Explor Target Antitumor Ther. 2022;3:149–171
    DOI: https://doi.org/10.37349/etat.2022.00077
    View:304
    Download:20
    Times Cited: 0
    Open Access
    Review
    New antibody-drug conjugates (ADCs) in breast cancer—an overview of ADCs recently approved and in later stages of development
    Antibody-drug conjugates (ADCs) have changed the treatment of breast cancer (BC) in more recent years. BC is a heterogenous group of malignancies with a broad range of histopathological characterist [...] Read more.
    Kira-Lee Koster ... Markus Joerger
    Published: February 24, 2022 Explor Target Antitumor Ther. 2022;3:27–36
    DOI: https://doi.org/10.37349/etat.2022.00069
    View:398
    Download:35
    Times Cited: 0
    Open Access
    Review
    Antibody-drug conjugate therapies in multiple myeloma—what’s next on the horizon?
    Targeted immunotherapy has arisen over the past decade to the forefront of cancer care. Notably, targeted therapies such as antibody-drug conjugates (ADCs) are becoming more recognized for a novel a [...] Read more.
    Monique Hartley-Brown, Paul Richardson
    Published: January 14, 2022 Explor Target Antitumor Ther. 2022;3:1–10
    DOI: https://doi.org/10.37349/etat.2022.00067
    View:515
    Download:74
    Times Cited: 0
    Open Access
    Original Article
    Physical characteristics comparison between maytansinoid-based and auristatin-based antibody-drug conjugates
    Aim: Direct analytical comparison of two major drug-linkers in the antibody-drug conjugate (ADC) field was conducted. Methods: Four different analytical methods [AlogP calculation, reverse phase (RP) high-performance liquid chrom [...] Read more.
    Tomohiro Fujii ... Yutaka Matsuda
    Published: December 31, 2021 Explor Target Antitumor Ther. 2021;2:576–585
    DOI: https://doi.org/10.37349/etat.2021.00064
    View:578
    Download:56
    Times Cited: 0