Prof. Thomas Efferth E-Mail
Director, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Germany
The skin is a indispensable barrier between the inside of an organism to the outer world. Breaking this barrier can have severe consequences for an organism. Similar conditions apply for interior wounds. Therefore, mechanisms of healing wounds are of tremendous importance. The healing process comprises of several stages, i.e., blood clotting, inflammation, cellular growth and skin remodeling. There are certain diseases that hamper proper wound healing, e.g., diabetes, metabolic diseases, infections etc. leading to healing failures and chronic wounds. Considering the importance of wound healing processes, it comes as no surprise that research on this topic is a hot topic. During the past years, innovative and exciting scientific concepts have been delineated to offer new possibilities for healing wounds, including cellular plasticity by stem cells, tissue regeneration, scarless wound healing, tissue restoration in tumor diseases, and many more.
With the current special issue, we provide a forum to open an interdisciplinary discussion for scientists and clinicians from diverse disciplines to present innovative and thriving concepts to better understand current concepts and innovations in wound healing. We welcome manuscript from diverse fields such as all related disciplines in medicine as well as pharmacology (of synthetic and natural compounds), immunology, cell and molecular biology, systems and network pharmacology, etc. dealing with wound healing.
The aim is to provide a comprehensive overview of the current understanding and to span a bow from basic to translational and clinical aspects. This special issue should enable the reader to gain the fundamental knowledge of current cutting-edge research.
Keywords: Dermatology, immunology, stem cell biology, targeted therapy