• 5 results in Exploration of Medicine
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    Nanomedicine in cancer therapy: promises and hurdles of polymeric nanoparticles
    The limitations of current cancer treatments have stimulated the application of nanotechnology to develop more effective and safer cancer therapies. Remarkable progress has been made in the development of nanomedicine to overcome  [...] Read more.
    Carmen Paus ... Alessandra Cambi
    Published: April 30, 2021 Explor Med. 2021;2:167–185
    DOI: https://doi.org/10.37349/emed.2021.00040
    This article belongs to the special issue Nanomedicine and Cancer Immunotherapy
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    Open Access
    Review
    AS1411-functionalized delivery nanosystems for targeted cancer therapy
    Nucleolin (NCL) is a multifunctional nucleolar phosphoprotein harboring critical roles in cells such as cell proliferation, survival, and growth. The dysregulation and overexpression of NCL are related to various pathologic and on [...] Read more.
    Pooria Safarzadeh Kozani ... Mohammad Tariq Malik
    Published: April 30, 2021 Explor Med. 2021;2:146–166
    DOI: https://doi.org/10.37349/emed.2021.00039
    This article belongs to the special issue Nanomedicine and Cancer Immunotherapy
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    Open Access
    Original Article
    Angiotensin-(3-4) modulates the overweight- and undernutrition-induced ACE2 downregulation in renal proximal tubule cells: implications for COVID-19?
    Aim: The renal lesions–including severe acute kidney injury–are severe outcomes in severe acute respiratory syndrome coronavirus 2 infections. There are no reports regarding the influence of the nutritional status on the sever [...] Read more.
    Rafael Luzes ... Adalberto Vieyra
    Published: April 30, 2021 Explor Med. 2021;2:135–145
    DOI: https://doi.org/10.37349/emed.2021.00038
    This article belongs to the special issue Angiotensins—A Century of Progress
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    Open Access
    Case Report
    Hepatic manifestations of drug reaction with eosinophilia and systemic symptoms syndrome
    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening drug reaction, which can affect multiple organs. Patients with DRESS syndrome and hepatic manifestations may present alterati [...] Read more.
    Maria Gabriela Delgado ... Jean François Dufour
    Published: April 30, 2021 Explor Med. 2021;2:122–134
    DOI: https://doi.org/10.37349/emed.2021.00037
    This article belongs to the special issue Exploring Chronic Liver Disease
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    Times Cited: 0
    Open Access
    Original Article
    Proof of concept: digital clock drawing behaviors prior to transcatheter aortic valve replacement may predict length of hospital stay and cost of care
    Aims: Reduced pre-operative cognitive functioning in older adults is a risk factor for postoperative complications, but it is unknown if preoperative digitally-acquired clock drawing test (CDT) cognitive screening variables, which [...] Read more.
    Margaret Ellenora Wiggins ... Catherine C. Price
    Published: March 05, 2021 Explor Med. 2021;2:110–121
    DOI: https://doi.org/10.37349/emed.2021.00036
    This article belongs to the special issue Digital Biomarkers: The New Frontier for Medicine and Research
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