• Special Issue Topic

    Bioinformatics, Big Data, AI: Exploring Immunology

    Submission Deadline: July 10, 2023

    Guest Editor

    Dr. Pierre-Antoine Gourraud E-Mail

    Professor of Medicine, Faculty of Medicine / Department, of Public Health Université de Nantes/ ITUN Leader of ATIP-Avenir Team 5

    Research Keywords: Biostatistics, bioinformatics, biomedical data warehouse, genetic, immunology, epidemiology

    About the Special Issue

    Immunology is often cited as a recent discipline that has been at the forefront of biology through biotechnological innovations in human and animal health. In many situations, the modern framework of systems biology to approach living phenomena finds examples in immunology. This is so much true that immunology itself, because it is everywhere, is in danger of losing its own identity. Immunology has also invented the collaborative framework for sharing experience, experimental resources and now bioinformatics resources in the dual form of data and computational tools. Immunology is at the crossroad of data-driven evidence: All the way from genetic contribution to immunology to decision making in care management, bioinformatics has become crucial. Immunology is also a fertile field for developing new tools and resources in bioinformatics because it often engages more than one individual player: host and pathogens in infections, donor and recipients in transplantation, the evolving distinction between self and non-self in immune system devilment evolution and learning.

    In this special issue of Exploring Immunology, we want to address how bioinformatics tools are essential for structuring data resources and implementing algorithms. These tools have often become essential for cutting-edge science, whether bioinformatics tools or data resources are transforming basic science or have direct application in translational science. The editorial board therefore welcomes contributions, concepts, and solutions including new ideas for presenting or organizing data resources in immunology, as well as validation of a bioinformatics data processing pipeline that could be transferred to other situations and the translational application of bioinformatics in immunology in general.

    Keywords: Immunology, bioinformatics, data resources

    Call for Papers

    Published Articles

    Open Access
    Beyond MHC binding: immunogenicity prediction tools to refine neoantigen selection in cancer patients
    In the last years, multiple efforts have been made to accurately predict neoantigens derived from somatic mutations in cancer patients, either to develop personalized therapeutic vaccines or to stud [...] Read more.
    Ibel Carri ... María Marcela Barrio
    Published: April 25, 2023 Explor Immunol. 2023;3:82–103
    DOI: https://doi.org/10.37349/ei.2023.00091
    Open Access
    Immunoinformatics and tick vaccinology
    Immunoinformatics is an emerging area focused on development and applications of methods used to facilitate vaccine development. There is a growing interest in the field of vaccinology cente [...] Read more.
    Rodrigo Rosario-Cruz ... Fernando Rosario-Domínguez
    Published: February 24, 2023 Explor Immunol. 2023;3:1–16
    DOI: https://doi.org/10.37349/ei.2023.00085
    Times Cited: 0
    Open Access
    Original Article
    Distributing human leukocyte antigen (HLA) database in histocompatibility: a shift in HLA data governance
    Aim: Human leukocyte antigen (HLA) population genetics has been a historical field centralizing data resource. HLA genetics databases typically facilitate access to frequencies of allele, haploty [...] Read more.
    Sirine Sayadi ... Pierre-Antoine Gourraud
    Published: November 01, 2022 Explor Immunol. 2022;2:749–759
    DOI: https://doi.org/10.37349/ei.2022.00080
    Times Cited: 0