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    Cell Biology and Treatment of Autoimmune Diseases

    Submission Deadline: July 31, 2023

    Guest Editor

    Dr. Thomas Efferth E-Mail

    Director, Institute of Pharmaceutical and Biomedical Sciences, Johannes-Gutenberg University of Mainz, Mainz, Germany


    About the Special Issue

    The immune system is indispensable for the defense against microbes, but on the other hand a deregulated immune function can be directed against the body’s own structures leading to an estimated 80-100 different diseases. They can be located nearly everywhere in the body ranging from mild to severe, e.g., lupus erythematosus, inflammatory bowel disease, rheumatoid arthritis, diabetes mellitus type 1 to mention but a few. Autoimmune diseases can severely hamper the quality of life. 

    Despite tremendous efforts to understand the pathogenesis and to improve clinical therapy and outcome, a causative cure for these diseases still does not appear at the horizon, although much progress has been made to manage the symptoms of autoimmune diseases (e.g., NSAIDS, glucocorticoids, DMARDS) More recently, therapeutic antibodies, antigen-specific immunotherapy, regulatory T-cell therapy etc. came into the focus. 

    We welcome manuscript from diverse fields such as immunology, all related disciplines in medicine as well as pharmacology (of synthetic and natural compounds), medicinal chemistry, molecular biology, systems and network pharmacology, etc. dealing with autoimmune diseases. 

    The aim is to provide a comprehensive overview of the current understanding and to span a bow from basic to translational and clinical aspects. This special issue should enable the reader to gain the fundamental knowledge of current cutting-edge research.  


    Keywords: Immunology, immune therapy, monoclonal antibodies, targeted therapy

    Call for Papers

    Published Articles

    • Submit a Manuscript
    • Aims and Scope
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    • Ongoing Special Issues
      New insights in cancer immunology: the role of microbiota from immunosurveillance to immunotherapy
      Immunology, Immunopathology and Genomics of SARS-COV-2
      Interplay of Stem Cells and Immunology in Regenerative Medicine
      Cytokines and Skin Diseases
      DNA Sensing in Lung Inflammation
      The Role of Adaptor Proteins in Lymphoid Cell Signaling
      Nanomaterials interaction with chemokines: perspectives for applied immunology
      Old and New Paradigms in Viral Vaccinology
      Autoantibodies Associated to Thrombosis and Hemostasis
      Immunosenescence: Mechanisms and Its Impact
      The Complement System in Health and Disease
      Chronic Inflammation and Autoimmunity
      Bioinformatics, Big Data, AI: Exploring Immunology
      Role of NK cells, Chemokines, and Pyroptosis in Melanoma Development or Treatment
      Immunoregulatory Function of Mesenchymal Stem Cells in Tissue Repair and Regeneration
      The Immune Signature of Microgravity
      Cell Biology and Treatment of Autoimmune Diseases
      Mucosal Immune Cells - Border Protection or Entrance Gate?
      Immunobiology of Dendritic Cells
      Neuroimmunology of Multiple Sclerosis: Exploring New Perspectives
      Physical Activity and Immune System in Chronic Diseases : Mechanisms and Insights
      Immunobiology and Inflammation in the Male Reproductive System
    • Completed Special Issues
      Cross Talk Among Skin Cells and Immune Cells
      Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
      Human Reproduction: Involvement of the Immune System
      Interplay of γδ T cells and Tumor Cells
      The‌ ‌Sepsis‌ ‌induced‌ ‌Immune‌ ‌Conundrum
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