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  • Special Issue Topic

    Immunoregulatory Function of Mesenchymal Stem Cells in Tissue Repair and Regeneration

    Submission Deadline: July 11, 2023

    Guest Editor

    Yong Jian Geng, MD, PhD E-Mail

    Professor (retired) of Medicine, the University of Texas Health Science Center at Houston, McGovern School of Medicine, and Professional Member, Texas Heart Institute, Houston, Texas, USA


    About the Special Issue

    Mesenchymal stem cells (MSCs) are a class of self-renewable multipotent stem cells, which exist in most of adult tissues and organs. In a juxtacrine or paracrine manner, MSCs possess an immunoregulatory property, involved in phenotypic change and injury-response of immune cells during the process of tissue repair and regeneration. In response to tissue injury and environmental insults, MSCs produce various pro-angiogenic factors and promote neo-vascularization in wound healing, and promote repair and regeneration. This special issue is aimed to update current knowledge and provide new research evidence about the molecular mechanisms that regulate the crosstalk between MSCs and immune cells in tissue repair and regeneration. 

    We welcome reports from both basic laboratory research and clinical investigation as well as minireview and processing on related topics.

    Keywords: Mesenchymal stem cells; immune regulation; stroma; wound healing; cytokines; vascularization; epigenetics

    Call for Papers

    Published Articles

    • Submit a Manuscript
    • Aims and Scope
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    • Ongoing Special Issues
      New insights in cancer immunology: the role of microbiota from immunosurveillance to immunotherapy
      Immunology, Immunopathology and Genomics of SARS-COV-2
      Interplay of Stem Cells and Immunology in Regenerative Medicine
      Cytokines and Skin Diseases
      DNA Sensing in Lung Inflammation
      The Role of Adaptor Proteins in Lymphoid Cell Signaling
      Nanomaterials interaction with chemokines: perspectives for applied immunology
      Old and New Paradigms in Viral Vaccinology
      Autoantibodies Associated to Thrombosis and Hemostasis
      Immunosenescence: Mechanisms and Its Impact
      The Complement System in Health and Disease
      Chronic Inflammation and Autoimmunity
      Bioinformatics, Big Data, AI: Exploring Immunology
      Role of NK cells, Chemokines, and Pyroptosis in Melanoma Development or Treatment
      Immunoregulatory Function of Mesenchymal Stem Cells in Tissue Repair and Regeneration
      The Immune Signature of Microgravity
      Cell Biology and Treatment of Autoimmune Diseases
      Mucosal Immune Cells - Border Protection or Entrance Gate?
      Immunobiology of Dendritic Cells
      Neuroimmunology of Multiple Sclerosis: Exploring New Perspectives
      Physical Activity and Immune System in Chronic Diseases : Mechanisms and Insights
      Immunobiology and Inflammation in the Male Reproductive System
    • Completed Special Issues
      Cross Talk Among Skin Cells and Immune Cells
      Vaccine-induced Immune Responses Against SARS-CoV-2 Infections
      Human Reproduction: Involvement of the Immune System
      Interplay of γδ T cells and Tumor Cells
      The‌ ‌Sepsis‌ ‌induced‌ ‌Immune‌ ‌Conundrum
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