Exploration of Drug Science

Open Access Original Article

Controlled release of dexamethasone phosphate from modified mesoporous biocompatible silica nanoparticles: synthesis, characterization, and kinetic studies

Juan Manuel Galdopórpora ... María Victoria Tuttolomondo

Published: February 28, 2025 Explor Drug Sci. 2025;3:100895

DOI: https://doi.org/10.37349/eds.2025.100895

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2710 73 0

Open Access Original Article

Prediction of drug exposure in hepatic impairment: a comparison between minimal physiologically based pharmacokinetic (mPBPK) and whole body PBPK models

Iftekhar Mahmood

Published: February 27, 2025 Explor Drug Sci. 2025;3:100894

DOI: https://doi.org/10.37349/eds.2025.100894

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1909 77 1

Open Access Review

Critical review on nutritional, bioactive and medicinal potential of Bunium persicum

Prachi Bhatt ... Mamta Baunthiyal

Published: February 27, 2025 Explor Drug Sci. 2025;3:100893

DOI: https://doi.org/10.37349/eds.2025.100893

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3739 83 0

Open Access Review

Unlocking the therapeutic potential of protein kinase inhibitors in neurodegenerative and psychiatric disorders

Angela Asir R V ... Izhak Michaelevski

Published: February 26, 2025 Explor Drug Sci. 2025;3:100892

DOI: https://doi.org/10.37349/eds.2025.100892

This article belongs to the special issue Leveraging the FDA-Approved Kinase Inhibitors to Treat Neurological Disorders

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4227 124 1

Open Access Original Article

Behind anticancer molecules: lactoferricin dimeric peptides with fast, selective, persistent and broad-spectrum cytotoxic effect

Karen Johanna Cárdenas-Martínez ... Javier Eduardo García-Castañeda

Published: February 26, 2025 Explor Drug Sci. 2025;3:100891

DOI: https://doi.org/10.37349/eds.2025.100891

This article belongs to the special issue Bioactive Peptides: Pioneering Innovations in Latin American Research

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2430 85 1

Open Access Review

Ischemic stroke and post-stroke depression: the role of agomelatine

Aamna Arshad ... Bibek Giri

Published: February 25, 2025 Explor Drug Sci. 2025;3:100890

DOI: https://doi.org/10.37349/eds.2025.100890

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3859 84 1

Open Access Original Article

Control of diabetic nephropathy in male Wistar rats using ethanolic extract of Monodora myristica seeds and its biosynthesized selenium nanoparticles

Babalola Ola Yusuf ... Rasheed Bolaji Ibrahim

Published: February 19, 2025 Explor Drug Sci. 2025;3:100889

DOI: https://doi.org/10.37349/eds.2025.100889

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2189 57 0

Open Access Commentary

Recent exploration of γ-AApeptide based antimicrobial peptide mimics as potential therapeutics towards drug-resistant bacteria

Jarais Fontaine, Jianfeng Cai

Published: February 19, 2025 Explor Drug Sci. 2025;3:100888

DOI: https://doi.org/10.37349/eds.2025.100888

This article belongs to the special issue Bioactive Peptides discovery and development

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2367 58 0

Open Access Review

Combating antibiotic resistance: mechanisms, challenges, and innovative approaches in antibacterial drug development

Aiswarya M. Rajesh ... Rambabu Dandela

Published: January 26, 2025 Explor Drug Sci. 2025;3:100887

DOI: https://doi.org/10.37349/eds.2025.100887

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11834 246 1

Open Access Review

Lutein and inflammation: a comprehensive review of its mechanisms of action

Paradentavida Prathyusha ... Edakkadath R. Sindhu

Published: January 25, 2025 Explor Drug Sci. 2025;3:100885

DOI: https://doi.org/10.37349/eds.2025.100885

This article belongs to the special issue Remedial benefits of natural products in inflammation and cancer

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7978 206 5

Open Access Original Article

Lysozyme-based spray for treatment of radiotherapy-induced oral mucositis

Zdenka Gojković ... Una Glamočlija

Published: January 24, 2025 Explor Drug Sci. 2025;3:100886

DOI: https://doi.org/10.37349/eds.2025.100886

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2365 39 0

Open Access Mini Review

Advantages of using biofilms to obtain high-value molecules by microbial biotransformations

Nicoly Subtil de Oliveira ... Edvaldo Antonio Ribeiro Rosa

Published: January 14, 2025 Explor Drug Sci. 2025;3:100884

DOI: https://doi.org/10.37349/eds.2025.100884

This article belongs to the special issue Greening Drug Manufacturing for a Sustainable Healthcare

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3016 168 2

Open Access Mini Review

Impact of the crosstalk between the PTEN and PAFR as well as PAFR and EGFR pathways in cancer

Anita Thyagarajan ... Ravi P. Sahu

Published: January 14, 2025 Explor Drug Sci. 2025;3:100883

DOI: https://doi.org/10.37349/eds.2025.100883

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1863 71 0

Open Access Original Article

Phenylalanine-derived β-lactam TRPM8 antagonists: revisiting configuration and new benzoyl derivatives

Cristina Martín-Escura ... Rosario González-Muñiz

Published: January 13, 2025 Explor Drug Sci. 2025;3:100882

DOI: https://doi.org/10.37349/eds.2025.100882

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2074 64 1

Open Access Review

Sirtuin activators as an anti-aging intervention for longevity

Puja Sah ... Donkupar Syiem

Published: January 12, 2025 Explor Drug Sci. 2025;3:100881

DOI: https://doi.org/10.37349/eds.2025.100881

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23254 331 5

Open Access Review

What are biopharmaceuticals?

Abhay H. Pande ... J. Anakha

Published: January 10, 2025 Explor Drug Sci. 2025;3:100880

DOI: https://doi.org/10.37349/eds.2025.100880

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10068 279 1