Expression of GPX4 gene in normal tissue, histologically normal tissue and atypical hyperplasia. (A) Expression of GPX4 in atypical hyperplasia (AH, N = 17), corresponding histologically normal (HN, N = 17) tissue, and normal breast tissue (NOR, N = 4). (B) Expression of GPX4 in atypical lobular hyperplasia (ALH, N = 8), atypical ductal hyperplasia (ADH, N = 9), and corresponding HN tissue [respectively, HNL (HN lobular), N =8, and HND (HN ductal), N = 9]. The differences were evaluated by the unpaired Wilcoxon test; values of P < 0.05 were considered statistically significant, and marked as * (P < 0.05) and ** (P < 0.01)